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Hydrogen sulfide (H\n                    <jats:sub>2<\/jats:sub>\n                    S) and ammonia (NH\n                    <jats:sub>3<\/jats:sub>\n                    ) produced by decomposing\n                    <jats:italic>Sargassum<\/jats:italic>\n                    could be involved in airway obstruction and bronchial inflammation. The study was undertaken to evaluate the effects of exposure to H\n                    <jats:sub>2<\/jats:sub>\n                    S and NH\n                    <jats:sub>3<\/jats:sub>\n                    gases emitted during\n                    <jats:italic>Sargassum<\/jats:italic>\n                    decomposition based on measures of airflow obstruction and bronchial inflammation in a study population from the French Caribbean Island of Martinique. Ambient air exposure was estimated by the closest ground H\n                    <jats:sub>2<\/jats:sub>\n                    S\/NH\n                    <jats:sub>3<\/jats:sub>\n                    sensor. Lung function and bronchial inflammation were evaluated by spirometry and fractional measurement of nitric oxide in the exhaled air (FeNO), respectively. Multivariate logistic and linear regression were applied to analyze associations between cumulative\n                    <jats:italic>Sargassum<\/jats:italic>\n                    H\n                    <jats:sub>2<\/jats:sub>\n                    S\/NH\n                    <jats:sub>3<\/jats:sub>\n                    exposure and risk of airway obstruction and FeNO changes. The analyses also took into account the effects of confounding factors, notably air pollution. Among the 335 study patients, 72% were living in\n                    <jats:italic>Sargassum<\/jats:italic>\n                    \u2010impacted zones. Compared with nonexposed patients, exposed patients had lung measures showing airway obstruction and increased FeNO levels. Exposed patients with asthma presented a two\u2010fold rise in FeNO levels. Multivariate modeling retained mean cumulative concentrations of\n                    <jats:italic>Sargassum<\/jats:italic>\n                    H\n                    <jats:sub>2<\/jats:sub>\n                    S and NH\n                    <jats:sub>3<\/jats:sub>\n                    as independent predictors of increased risk of airway obstruction and bronchial inflammation. The present study highlights a potential association between impaired lung function and exposure to\n                    <jats:italic>Sargassum<\/jats:italic>\n                    H\n                    <jats:sub>2<\/jats:sub>\n                    S and NH\n                    <jats:sub>3<\/jats:sub>\n                    during coastal stranding episodes. Present study results strongly support the deleterious effect on the respiratory health of individuals chronically exposed to\n                    <jats:italic>Sargassum<\/jats:italic>\n                    gas emissions.\n                  <\/jats:p>","DOI":"10.1002\/tox.70110","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T01:28:43Z","timestamp":1777253323000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<i>Sargassum<\/i>\n                    Lung Syndrome: Air Flow Obstruction and Bronchial Inflammation Are Observed After Prolonged Exposure to\n                    <i>Sargassum<\/i>\n                    Gas Emissions in the Eastern Caribbean"],"prefix":"10.1002","author":[{"given":"Rishika","family":"Banydeen","sequence":"first","affiliation":[{"name":"Cardiovascular Research Team (UR5_3 PC2E) University of the French West Indies (Universit\u00e9 des Antilles)  Fort\u2010de\u2010France France"},{"name":"Department of Toxicology and Critical Care Medicine University Hospital of Martinique (CHU Martinique)  Fort\u2010de\u2010France France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Florentin","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Team (UR5_3 PC2E) University of the French West Indies (Universit\u00e9 des Antilles)  Fort\u2010de\u2010France France"},{"name":"Department of Toxicology and Critical Care Medicine University Hospital of Martinique (CHU Martinique)  Fort\u2010de\u2010France France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxime","family":"Boutourlinsky","sequence":"additional","affiliation":[{"name":"Department of General Medicine University Hospital of Martinique (CHU Martinique)  Fort\u2010de\u2010France 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