{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T20:10:14Z","timestamp":1780603814511,"version":"3.54.1"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T00:00:00Z","timestamp":1704326400000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R33 AG062867"],"award-info":[{"award-number":["R33 AG062867"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["A&amp;D Transl Res &amp; Clin Interv"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION<\/jats:title>\n                    <jats:p>This study aimed to understand whether older adults\u2019 longitudinal completion of assessments in an online Alzheimer's disease and related dementias (ADRD)\u2013related registry is influenced by self\u2010reported medical conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>\n                      Brain Health Registry (BHR) is an online cognitive aging and ADRD\u2010related research registry that includes longitudinal health and cognitive assessments. Using logistic regressions, we examined associations between longitudinal registry completion outcomes and self\u2010reported (1) number of medical conditions and (2) eight defined medical condition groups (cardiovascular, metabolic, immune system, ADRD, current psychiatric, substance use\/abuse, acquired, other specified conditions) in adults aged 55+ (\n                      <jats:italic>N =<\/jats:italic>\n                      23,888). Longitudinal registry completion outcomes were assessed by the completion of the BHR initial questionnaire (first questionnaire participants see at each visit) at least twice and completion of a cognitive assessment (Cogstate Brief Battery) at least twice. Models included ethnocultural identity, education, age, and subjective memory concern as covariates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>We found that the likelihood of longitudinally completing the initial questionnaire was negatively associated with reporting a diagnosis of ADRD and current psychiatric conditions but was positively associated with reporting substance use\/abuse and acquired medical conditions. The likelihood of longitudinally completing the cognitive assessment task was negatively associated with number of reported medical conditions, as well as with reporting cardiovascular conditions, ADRD, and current psychiatric conditions. Previously identified associations between ethnocultural identity and longitudinal assessment completion in BHR remained after accounting for the presence of medical conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION<\/jats:title>\n                    <jats:p>This post hoc analysis provides novel, initial evidence that older adults\u2019 completion of longitudinal assessments in an online registry is associated with the number and types of participant\u2010reported medical conditions. Our findings can inform future efforts to make online studies with longitudinal health and cognitive assessments more usable for older adults with medical conditions. The results need to be interpreted with caution due to selection biases, and the under\u2010inclusion of minoritized communities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/trc2.12438","type":"journal-article","created":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T02:43:32Z","timestamp":1704422612000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Participant completion of longitudinal assessments in an online cognitive aging registry: The role of medical conditions"],"prefix":"10.1002","volume":"10","author":[{"given":"Miriam T.","family":"Ashford","sequence":"first","affiliation":[{"name":"VA Advanced Imaging Research Center San Francisco Veteran's Administration Medical Center  San Francisco California USA"},{"name":"Department of Veterans Affairs Medical Center Northern California Institute for Research and Education (NCIRE)  San Francisco California 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