{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T12:29:38Z","timestamp":1774441778551,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T00:00:00Z","timestamp":1721606400000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01AG067541"],"award-info":[{"award-number":["R01AG067541"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R24AG063718"],"award-info":[{"award-number":["R24AG063718"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P30AG072972"],"award-info":[{"award-number":["P30AG072972"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000957","name":"Alzheimer's Association","doi-asserted-by":"publisher","award":["AARGD\u201019\u2010619832"],"award-info":[{"award-number":["AARGD\u201019\u2010619832"]}],"id":[{"id":"10.13039\/100000957","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["A&amp;D Transl Res &amp; Clin Interv"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>There is a dearth of research on cognitive aging and dementia in Asian Americans, particularly in Vietnamese Americans, the fourth largest Asian subgroup in the United States.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Vietnamese Insights into Cognitive Aging Program (VIP) investigates early life adversity and war\u2010related trauma and their associations with cognitive health in a community\u2010based sample of older Vietnamese Americans in Northern California (i.e., Sacramento and Santa Clara counties). Baseline measurements include a comprehensive neuropsychological battery, including measures of global cognition along with executive function, semantic memory, and episodic memory. Data also include measures of functioning, early life adversity and trauma exposure, and psychosocial and traditional cardiovascular disease risk factors. Cognitive assessments will be repeated twice over the course of the data collection period, approximately 12\u2010 and 24\u2010 months post\u2010baseline. Blood samples collected during Wave 2 will be assayed for biochemical risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Baseline assessments were conducted from January 2022 to November 2023, with\n                      <jats:italic>N<\/jats:italic>\n                      \u00a0=\u00a0548 Vietnamese Americans; mean age \u00b1 SD was 73 \u00b1 5.31 years and 55% of participants were women. There were significant differences in social factors by site, with Santa Clara participants having higher education (some college or higher: Sacramento, \u224825%; Santa Clara: \u224848%) and marginally higher incomes compared to Sacramento participants. A higher percentage of Santa Clara participants reported speaking English well or very well (24%) compared to Sacramento participants (13%), although the majority of the entire sample (81%) reported speaking some to no English (response options: not at all; some\/a little bit; well\/very well).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This longitudinal study providea a unique opportunity to more fully delineate psychosocial factors that contribute to dementia disparities in diverse and under\u2010engaged populations. Future work will examine cognition, the prevalence of mild cognitive impairment and dementia, and other health outcomes, while controlling for site differences in all analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>Vietnamese Insights into Cognitive Aging Program (VIP) is a new study.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>VIP has detailed early life and health data on 548 older Vietnamese Americans.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>History of war and trauma may contribute to Alzheimer's disease and related dementias (ADRD)\u2013related burden.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>VIP may provide insight into ADRD burden in other understudied groups.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/trc2.12494","type":"journal-article","created":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T10:25:14Z","timestamp":1721643914000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Vietnamese Insights into Cognitive Aging Program (VIP): Objectives, study design, and cohort description"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1093-0477","authenticated-orcid":false,"given":"Oanh L.","family":"Meyer","sequence":"first","affiliation":[{"name":"School of Medicine University of California, Davis  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USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ladson","family":"Hinton","sequence":"additional","affiliation":[{"name":"School of Medicine University of California, Davis  Sacramento California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quyen Q.","family":"Tiet","sequence":"additional","affiliation":[{"name":"Clinical Psychology Program California School of Professional Psychology at Alliant International University  Emeryville California USA"},{"name":"National Center for PTSD Dissemination and Training Division VA Palo Alto Health Care System  Menlo Park California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quyen","family":"Vuong","sequence":"additional","affiliation":[{"name":"International Children Assistance Network (ICAN)  San Jose California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon","family":"Gavett","sequence":"additional","affiliation":[{"name":"School of Medicine 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