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A comprehensive search was conducted in EMBASE, PubMed, EconLit, Web of Science, Cumulative Index to Nursing and Allied Health (CINAHL), and The NHS Economic Evaluation Database (NHS EED). Publications were dually screened and assessed against eligibility criteria, and reporting quality was appraised using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) framework. Seventeen full EEs met the inclusion criteria; all were conducted in high\u2010income countries and covered strategies in identification (29%), risk reduction (65%), and other strategies (6%). The number of publications from 2016 to 2025 tripled compared to the preceding periods. Most risk\u2010reduction strategies were cost\u2010effective and exhibited high reporting quality. The average reporting quality, based on the CHEERS framework, was 72%, with a noticeable improvement observed in articles published after 2020. Overall, the findings suggest that most risk\u2010reduction strategies may offer good value for money. However, evidence remains limited, specifically in low\u2010 and middle\u2010income countries; therefore, additional EEs are needed to guide future investment in strategies targeting pre\u2010diagnosis dementia populations.<\/jats:p>","DOI":"10.1002\/trc2.70236","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T03:38:48Z","timestamp":1779421128000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Economic evaluations of strategies targeting pre\u2010diagnosis dementia populations: A systematic review"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8187-8277","authenticated-orcid":false,"given":"Men Thi","family":"Hoang","sequence":"first","affiliation":[{"name":"School of Medicine Trinity College Dublin  Dublin Ireland"},{"name":"Faculty of Business Administration Van Lang University  Ho Chi Minh City Vietnam"},{"name":"Manchester Centre for Health Economics, Division of Population Health, Health Services Research &amp; Primary Care University of Manchester  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8392-3028","authenticated-orcid":false,"given":"Alina Mona","family":"Zenker","sequence":"additional","affiliation":[{"name":"Trinity College Institute of Neuroscience Trinity College Dublin  Dublin Ireland"},{"name":"Health Economics Unit, Department of Clinical Science (Malm\u00f6) Lund University  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjib","family":"Saha","sequence":"additional","affiliation":[{"name":"Health Economics Unit, Department of Clinical Science (Malm\u00f6) Lund University  Lund Sweden"},{"name":"Global Brain Health Institute Trinity College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulf\u2010G\u00f6ran","family":"Gerdtham","sequence":"additional","affiliation":[{"name":"Health Economics Unit, Department of Clinical Science (Malm\u00f6) Lund University  Lund Sweden"},{"name":"Department of Economics Lund University  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1421-2966","authenticated-orcid":false,"given":"Dominic","family":"Tr\u00e9pel","sequence":"additional","affiliation":[{"name":"School of Medicine Trinity College Dublin  Dublin Ireland"},{"name":"Trinity College Institute of Neuroscience Trinity College Dublin  Dublin Ireland"},{"name":"Global Brain Health Institute Trinity College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,21]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"World Health Organization.Dementia. 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