{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T03:14:32Z","timestamp":1788146072205,"version":"build-2803163510"},"reference-count":50,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T00:00:00Z","timestamp":1775433600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P30AG059305"],"award-info":[{"award-number":["P30AG059305"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["A&amp;amp;D Transl Res &amp;amp; Clin Interv"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>Translational equity means ensuring that diagnostics, treatments, care models, and prevention strategies are developed and implemented so they work for populations with the greatest burden and least access to care. In Alzheimer's disease and related dementias (ADRD), where most evidence derives from highly educated, non\u2010Hispanic White participants at large academic centers, translational equity is critical to prevent misclassification, limited access, and widening disparities and to ensure that underrepresented communities shape how new knowledge moves into practice. Hispanic and other populations in the United States are disproportionately affected by ADRD yet remain underrepresented in research, with gaps especially pronounced in high\u2010poverty border regions such as the Rio Grande Valley (RGV) of South Texas. We describe the design and early outcomes of the Rio Grande Valley Alzheimer's Disease Resource Center for Minority Aging Research (RGV AD\u2010RCMAR), a National Institute on Aging\u2010funded P30 center located at a new, R2, Hispanic\u2010Serving Institution. Drawing on program documents, center evaluation data, and alignment with national RCMAR statistics, we examine how the RGV AD\u2010RCMAR's three cores, the Leadership and Administrative Core, Analysis Core, and Community Liaison and Recruitment Core (CLRC), and the Research Education Component (REC) were structured to decentralize where dementia research questions are generated, who leads that work, and how benefits flow back to the community. During the 2018 to 2023 cycle, the RGV center supported 14 early\u2010career investigators, representing \u223c5% of all scientists in the national RCMAR\/AD\u2010RCMAR portfolio and \u223c12% of all AD\u2010RCMAR scientists. The REC maintained 50% female representation, retained 70% of scholars at the institution after pilot funding, and saw scholars secure National Institutes of Health (NIH) K\u2010 and R\u2010level awards. The CLRC has built a registry of over 600 residents interested in participation and documented hundreds of engagement activities and community changes, positioning the RGV AD\u2010RCMAR as a border\u2010based model for translational equity in AD\/ADRD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/trc2.70238","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T06:12:37Z","timestamp":1775542357000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Decentralizing dementia research to the US\u2013Mexico border: the Rio Grande Valley AD\u2010RCMAR as a model for translational equity"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5690-8833","authenticated-orcid":false,"given":"Gladys E.","family":"Maestre","sequence":"first","affiliation":[{"name":"Memory and Aging Center Institute of Neuroscience Neuro &amp; Behavioral Health Integrated Service Unit School of Medicine University of Texas Rio Grande Valley Harlingen Texas USA"},{"name":"South Texas Diabetes and Obesity Institute College of Science University of Texas Rio Grande Valley  Brownsville Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Blangero","sequence":"additional","affiliation":[{"name":"South Texas Diabetes and Obesity Institute College of Science University of Texas Rio Grande Valley  Brownsville Texas USA"},{"name":"Department of Human Genetics College of Science University of Texas Rio Grande Valley  Brownsville Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eron G.","family":"Manusov","sequence":"additional","affiliation":[{"name":"South Texas Diabetes and Obesity Institute College of Science University of Texas Rio Grande Valley  Brownsville Texas USA"},{"name":"Department of Human Genetics College of Science University of Texas Rio Grande Valley  Brownsville Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel A.","family":"de Erausquin","sequence":"additional","affiliation":[{"name":"Laboratory of Brain Modulation and Repair Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases University of Texas Health San Antonio  San Antonio Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Psychiatry School of Medicine University of Texas Rio Grande Valley  Harlingen Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Mej\u00eda\u2010Arango","sequence":"additional","affiliation":[{"name":"Memory and Aging Center Institute of Neuroscience Neuro &amp; Behavioral Health Integrated Service Unit School of Medicine University of Texas Rio Grande Valley Harlingen Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Diego","sequence":"additional","affiliation":[{"name":"South Texas Diabetes and Obesity Institute College of Science University of Texas Rio Grande Valley  Brownsville Texas USA"},{"name":"Department of Human Genetics College of Science University of Texas Rio Grande Valley  Brownsville Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"L\u00f3pez\u2010Alvarenga","sequence":"additional","affiliation":[{"name":"Division of Population Health &amp; Biostatistics School of Medicine University of Texas Rio Grande Valley  Edinburg Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Alaniz","sequence":"additional","affiliation":[{"name":"Memory and Aging Center Institute of Neuroscience Neuro &amp; Behavioral Health Integrated Service Unit School of Medicine University of Texas Rio Grande Valley Harlingen Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neyra","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Memory and Aging Center Institute of Neuroscience Neuro &amp; Behavioral Health Integrated Service Unit School of Medicine University of Texas Rio Grande Valley Harlingen Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9019-2768","authenticated-orcid":false,"given":"Rosa V.","family":"Pirela","sequence":"additional","affiliation":[{"name":"Memory and Aging Center Institute of Neuroscience Neuro &amp; Behavioral Health Integrated Service Unit School of Medicine University of Texas Rio Grande Valley Harlingen Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Tsin","sequence":"additional","affiliation":[{"name":"Memory and Aging Center Institute of Neuroscience Neuro &amp; Behavioral Health Integrated Service Unit School of Medicine University of Texas Rio Grande Valley Harlingen Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C.","family":"Mahaney","sequence":"additional","affiliation":[{"name":"South Texas Diabetes and Obesity Institute College of Science University of Texas Rio Grande Valley  Brownsville Texas USA"},{"name":"Department of Human Genetics College of Science University of Texas Rio Grande Valley  Brownsville Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,6]]},"reference":[{"issue":"5","key":"e_1_2_9_2_1","article-title":"2025 Alzheimer's disease facts and figures","volume":"21","author":"Alzheimer's Association","year":"2025","journal-title":"Alzheimers Dement"},{"key":"e_1_2_9_3_1","unstructured":"Alzheimer's Association. 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