{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:24:03Z","timestamp":1791397443463,"version":"4.3.3"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T00:00:00Z","timestamp":1709856000000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["UEG Journal"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Alcohol\u2010related liver disease (ALD) represents the most common indication for liver transplantation (LT) worldwide. Outcomes of LT for ALD are comparable with those of LT for other etiologies; however, ALD is still considered a controversial indication for LT, mainly because it is considered a self\u2010inflicted disease with a high risk of return to alcohol use after LT. Pre\u2010LT evaluation criteria have changed over time, with a progressive re\u2010evaluation of the required pre\u2010transplant duration of abstinence. Despite the fact that some transplant programs still require 6\u00a0months of abstinence in order to consider a patient suitable for LT, there is increasing evidence that a pre\u2010transplant abstinence period of &lt;6\u00a0months can be considered for well\u2010selected patients. Early LT for severe alcohol\u2010related hepatitis that has not responded to medical therapy has been shown to be an effective therapeutic option with high survival benefit when performed within strict and well\u2010recognized criteria. However, high variability in LT access exists for these patients due to the presence of social and medical stigma. A psycho\u2010social assessment, together with an evaluation by an addiction specialist, should be mandatory in patients with ALD who are potential candidates for LT in order to assess the risk of post\u2010transplant return to alcohol use and to ensure good long\u2010term outcomes. Finally, before LT, attention should be paid to the presence of other potential comorbidities (i.e., cardiovascular and neurological diseases), which could represent a potential contraindication to LT. Similarly, after LT, patients should be adequately monitored for the development of cardiovascular events and screened for \u201cde novo\u201d tumors, although standardized protocols for this monitoring do not exist at this time.<\/jats:p>","DOI":"10.1002\/ueg2.12548","type":"journal-article","created":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T04:45:14Z","timestamp":1709873114000},"page":"203-209","source":"Crossref","is-referenced-by-count":4,"title":["Workup and management of liver transplantation in alcohol\u2010related liver disease"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4332-2072","authenticated-orcid":false,"given":"Giacomo","family":"Germani","sequence":"first","affiliation":[{"name":"Multivisceral Transplant Unit Department of Surgery, Oncology and Gastroenterology Padua University Hospital  Padua 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