{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T13:42:35Z","timestamp":1791639755406,"version":"4.3.4"},"reference-count":52,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T00:00:00Z","timestamp":1715731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["UEG Journal"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The technical and clinical effectiveness of endoscopic ultrasonography (EUS)\u2010guided gastroenterostomy (GE) has been reported by several meta\u2010analyses, but few of them have addressed the adverse events (AE). The goal of the current meta\u2010analysis was to analyze the AEs associated with various types of EUS\u2010GE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All relevant studies reporting the AEs with EUS\u2010GE were searched from 2000 to 31st March 2023 in MEDLINE, Embase, and Scopus. The event rates were pooled using a random effects model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 36 studies (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a01846) were included in the meta\u2010analysis. The present meta\u2010analysis reports a pooled technical success rate of 96.9% (95.9\u201398.0;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>\n                        <jats:italic>2<\/jats:italic>\n                      <\/jats:sup>\n                      \u00a0=\u00a029.3%) with a pooled clinical success rate of 90.6% (88.5\u201392.7;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>\n                        <jats:italic>2<\/jats:italic>\n                      <\/jats:sup>\n                      \u00a0=\u00a060.9%). The pooled incidence of overall AEs with EUS\u2010GE was 13.0% (10.3\u201315.7;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>\n                        <jats:italic>2<\/jats:italic>\n                      <\/jats:sup>\n                      \u00a0=\u00a069.7%), with the commonest being maldeployment of the stent, seen in 4.6% (3.2\u20136.0;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>\n                        <jats:italic>2<\/jats:italic>\n                      <\/jats:sup>\n                      \u00a0=\u00a050.6%). The pooled incidences of serious AE and procedure\u2010related mortality were 1.2% (0.7\u20131.8;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>\n                        <jats:italic>2<\/jats:italic>\n                      <\/jats:sup>\n                      \u00a0=\u00a01.9%) and 0.3% (0.0\u20130.7;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>\n                        <jats:italic>2<\/jats:italic>\n                      <\/jats:sup>\n                      \u00a0=\u00a00.0%), respectively. Subgroup analysis of studies using only the free\u2010hand technique showed a significantly lower overall AE and maldeployment but not serious AE and other individual AEs. The pooled incidences of delayed stent migration and stent occlusion were 0.5% (0.0\u20131.1;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>\n                        <jats:italic>2<\/jats:italic>\n                      <\/jats:sup>\n                      \u00a0=\u00a00.0%) and 0.8% (0.2\u20131.3;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>\n                        <jats:italic>2<\/jats:italic>\n                      <\/jats:sup>\n                      \u00a0=\u00a00.0%), respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Despite a technical and clinical success rate of &gt;90%, AEs are seen in around one\u2010seventh of the cases of EUS\u2010GE, maldeployment being the commonest. However, the pooled incidence of serious AE and mortality remains low, which is reassuring.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ueg2.12576","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T05:10:19Z","timestamp":1715749819000},"page":"879-890","source":"Crossref","is-referenced-by-count":24,"title":["Adverse events with endoscopic ultrasound\u2010guided gastroenterostomy for gastric outlet obstruction\u2014A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9626-5243","authenticated-orcid":false,"given":"Suprabhat","family":"Giri","sequence":"first","affiliation":[{"name":"Department of Gastroenterology &amp; Hepatology Kalinga Institute of Medical Sciences  Bhubaneswar India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidharth","family":"Harindranath","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology 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