{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T13:00:36Z","timestamp":1791896436246,"version":"4.3.4"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["UEG Journal"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Acute pancreatitis is a potentially life\u2010threatening inflammation of the pancreas, with a rising incidence in most countries. Recent studies have suggested that acute pancreatitis is associated with increased long\u2010term mortality. However, the extent to which this association is influenced by the development of chronic pancreatitis or comorbid conditions, such as malignant disease, remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the association between acute pancreatitis and long\u2010term all\u2010cause mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Swedish Pancreatitis Cohort (SwePan) was used, including all individuals with a first\u2010time episode of acute pancreatitis in Sweden between 1990 and 2019 who survived the index hospital stay and 1:10 matched pancreatitis\u2010free individuals from the general population. Multivariable conditional Cox proportional hazard models were used to compare mortality among individuals with acute pancreatitis compared with the matched pancreatitis\u2010free control group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 89,465 individuals discharged from hospital with acute pancreatitis and 890,837 matched pancreatitis\u2010free individuals were followed up for 10,155,039 person\u2010years (mean 10.0\u00a0years). There were 33,764 (37.7%) deaths among individuals with acute pancreatitis and 265,403 (29.8%) deaths among controls. In multivariable adjusted models, mortality was increased in individuals with acute pancreatitis throughout the follow\u2010up period, particularly among those with severe and non\u2010gallstone\u2010related acute pancreatitis as compared to the matched controls. These results remained statistically significant after censoring the follow\u2010up time for recurrent acute pancreatitis or a diagnosis of chronic pancreatitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Acute pancreatitis was associated with increased long\u2010term mortality, even after adjusting for comorbidities, including cancer, and censoring for recurrent acute pancreatitis or chronic pancreatitis. Future research should assess causes of death and focus on understanding long\u2010term morbidity to facilitate prevention through tailored follow\u2010up strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ueg2.12774","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T12:13:29Z","timestamp":1741695209000},"page":"640-649","source":"Crossref","is-referenced-by-count":20,"title":["Long\u2010Term Mortality in Acute Pancreatitis\u2014A Population\u2010Based Cohort Study"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9969-1643","authenticated-orcid":false,"given":"Daniel","family":"Selin","sequence":"first","affiliation":[{"name":"Department of Clinical Science, Intervention and Technology Karolinska Institutet  Stockholm Sweden"},{"name":"Centre for Clinical Research S\u00f6rmland Uppsala University  Eskilstuna 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