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The aim of this systematic review and meta\u2010analysis was to clarify how sugar consumption contributes to the risk of developing inflammatory bowel disease (IBD) using the most recently available data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A library informationist retrieved relevant articles from PubMed, EMBASE, CINAHL, Cochrane Central, Web of Science, and Scopus. Two independent reviewers screened the abstracts and full texts, yielding 45 studies for inclusion. Meta\u2010analyses estimated odd ratios using random effect models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>11 prospective and 34 retrospective studies reported data on sugar intake and IBD risk. Pooled analysis showed that added sugar intake was associated with increased risk of Crohn's disease (OR 1.66; 95% Cl 1.21\u20132.29; <jats:italic>n<\/jats:italic>\u00a0=\u00a0523,730; 14 studies) and ulcerative colitis (OR 1.59; 95% CI 1.25\u20132.02; <jats:italic>n<\/jats:italic>\u00a0=\u00a0787,228; 18 studies). Similarly, soda\/sweetened beverage intake was associated with increased risk of Crohn's disease (OR 1.58; 95% CI 1.18\u20132.12; <jats:italic>n<\/jats:italic>\u00a0=\u00a0328,716; 12 studies) and ulcerative colitis (OR 1.72; 95% CI 1.23\u20132.391; <jats:italic>n<\/jats:italic>\u00a0=\u00a0328,642; 13 studies).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Sugar and soda\/sweetened beverage intake were associated with an increased risk of developing both Crohn's disease and ulcerative colitis. Although additional prospective investigation is warranted, current data suggest that reduction of sugar consumption might help reduce the risk of inflammatory bowel disease.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ueg2.70047","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T14:40:24Z","timestamp":1750257624000},"page":"1379-1409","source":"Crossref","is-referenced-by-count":10,"title":["Dietary Sugar and Sweetened Beverage Intake Increases Inflammatory Bowel Disease Risk: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-1408-1920","authenticated-orcid":false,"given":"Isha","family":"Maniyar","sequence":"first","affiliation":[{"name":"Department of Medicine UCSF School of Medicine  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0430-694X","authenticated-orcid":false,"given":"Arpita","family":"Jajoo","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology &amp; Hepatology Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gala Godoy","family":"Brewer","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Miami School of Medicine  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preetha","family":"Iyengar","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases UCLA School of Medicine  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases UCLA School of Medicine  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Fasulo","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases UCLA School of Medicine  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3557-3568","authenticated-orcid":false,"given":"Jacob","family":"White","sequence":"additional","affiliation":[{"name":"Welch Library Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa","family":"Parian","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology &amp; Hepatology Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berkeley N.","family":"Limketkai","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases UCLA School of Medicine  Los Angeles California USA"},{"name":"Division of Clinical Nutrition UCLA School of Medicine  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"issue":"5","key":"e_1_2_10_2_1","first-page":"72","article-title":"Inflammatory Bowel Disease: Crohn\u2019s Disease and Ulcerative Colitis","volume":"113","author":"Wehkamp J.","year":"2016","journal-title":"Deutsches \u00c4rzteblatt International"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.14872"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2014.03.005"},{"issue":"12","key":"e_1_2_10_5_1","article-title":"The Epidemiology and Risk Factors of Inflammatory Bowel Disease","volume":"8","author":"Ye Y.","year":"2015","journal-title":"International Journal of Clinical and Experimental Medicine"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.988481"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu12051348"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2021.707795"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n1554"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.17149"},{"key":"e_1_2_10_11_1","unstructured":"Wells G. 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