{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T15:37:18Z","timestamp":1793288238497,"version":"4.5.0"},"reference-count":34,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T00:00:00Z","timestamp":1759536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T00:00:00Z","timestamp":1759536000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["UEG Journal"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sarcopenia is common in patients with liver cirrhosis and is an independent predictor of morbidity and mortality. This prospective study assessed the performance of rectus femoris muscle (RFM) ultrasound in patients with liver cirrhosis to identify those at risk for sarcopenia as defined by the combination of low muscle mass and low muscle strength.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>84 patients with liver cirrhosis hospitalized at a tertiary center (05\/22\u201002\/24) were included with 6\u2010month follow\u2010up. Within 24\u201348\u00a0h of admission hand grip strength, chair rise test (CRT), timed up and go (TUG), short physical performance battery (SPPB), rectus femoris muscle ultrasound, and bioelectrical impedance analysis (BIA) were assessed. Statistical analyses included receiver operating characteristic (ROC) curves, Kaplan\u2013Meier estimates, Cox regression, and competing risk analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Most (73.8%) patients had decompensated and mainly alcohol\u2010related liver cirrhosis. Thickness and cross\u2010sectional area of rectus femoris muscle (MT\n                      <jats:sub>RFM<\/jats:sub>\n                      \/CSA\n                      <jats:sub>RFM<\/jats:sub>\n                      ) were significantly (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.01 each) lower in more advanced disease by Child\u2010Pugh (CP) stage, also when normalized for height\n                      <jats:sup>2<\/jats:sup>\n                      . MT\n                      <jats:sub>RFM<\/jats:sub>\n                      \/height\n                      <jats:sup>2<\/jats:sup>\n                      and CSA\n                      <jats:sub>RFM<\/jats:sub>\n                      \/height\n                      <jats:sup>2<\/jats:sup>\n                      demonstrated good predictive value for BIA\u2010derived low muscle mass (ASMI\u00a0&lt;\u00a07\/5.7\u00a0kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ) or low phase angle\u00a0\u2264\u00a04.9\u00b0 (AUROC 0.727\u20130.770). Impaired physical performance, in terms of prolonged CRT and TUG test time was associated with reduced MT\n                      <jats:sub>RFM<\/jats:sub>\n                      or CSA\n                      <jats:sub>RFM<\/jats:sub>\n                      (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05 each), respectively. Higher muscle echogenicity correlated with poorer performance in TUG and SPPB. Low rectus femoris muscle mass was associated with shorter survival and sarcopenic (prolonged CRT and low MT\n                      <jats:sub>RFM<\/jats:sub>\n                      \/height\n                      <jats:sup>2<\/jats:sup>\n                      ) patients had a high 6\u2010month mortality risk (HR 7.188; 95% CI 2.249\u201322.978).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Rectus femoris muscle ultrasound is a feasible bedside method for identifying patients with liver cirrhosis at risk of sarcopenia. Sarcopenia as diagnosed by prolonged CRT together with low RFM mass by ultrasound is an independent predictor for 6\u2010month mortality, highlighting the clinical utility of RFM ultrasound in diagnosing sarcopenia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ueg2.70114","type":"journal-article","created":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T16:48:47Z","timestamp":1759596527000},"page":"1936-1945","source":"Crossref","is-referenced-by-count":7,"title":["Mortality Prediction by Bedside Rectus Femoris Muscle Ultrasound for Sarcopenia Diagnosis in Liver Cirrhosis"],"prefix":"10.1002","volume":"13","author":[{"given":"Sara","family":"De Monte","sequence":"first","affiliation":[{"name":"Division of Hepatology Department of Internal Medicine II University Hospital W\u00fcrzburg  W\u00fcrzburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Altmann","sequence":"additional","affiliation":[{"name":"Division of Hepatology 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