{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T03:18:57Z","timestamp":1790651937660,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:00:00Z","timestamp":1760313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:00:00Z","timestamp":1760313600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["UEG Journal"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Crohn's disease (CD) and ulcerative colitis (UC) are progressive inflammatory bowel diseases that often result in bowel damage, imposing a significant burden on patients with insufficient disease control due to the limited efficacy of current treatments or complex disease management. There are limited data on how disease monitoring informs treatment decisions in daily clinical practice. The IBD\u2010PODCAST study aimed to estimate the proportion of Crohn's disease and ulcerative colitis patients experiencing suboptimal disease control in a real\u2010world setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate disease monitoring practices and their impact on physicians' actions and treatment decisions for patients with suboptimal disease control.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A non\u2010interventional cross\u2010sectional study was conducted across 103 sites in 10 countries. Criteria for suboptimal disease control were based on STRIDE\u2010II criteria, adapted by an expert panel.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      2185 patients (Crohn's disease:\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a01,108, ulcerative colitis:\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a01077) with a mean (SD) age of 44.0 (14.8) years and disease duration of 12.4 (9.2) years were included. Suboptimal disease control was present in 52.2% of CD (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0578) and 44.3% of UC patients (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0477). Disease monitoring via imaging and\/or endoscopy over a 12\u2010month period was conducted in approximately 40% of the patients. In patients that were lacking annual monitoring via imaging\/endoscopy and\/or biochemical monitoring at index, an optimal disease status indicating no objective inflammation was observed in only 31.1% of CD and 36.4% of UC patients. In patients with suboptimal disease control, 391 CD (67.6%) and 324 UC (67.9%) had clinically relevant parameters. In around 50% of these patients, physicians took action.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Annual disease monitoring via imaging\/endoscopy was performed in only 40% of inflammatory bowel disease patients. Physicians modified treatment in approximately half of patients with suboptimal disease control and clinically relevant parameters. The study emphasized the importance of consistent monitoring and taking action when targets are not met to improve the quality of life of patients with inflammatory bowel disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ueg2.70117","type":"journal-article","created":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T03:09:01Z","timestamp":1760411341000},"page":"1984-1998","source":"Crossref","is-referenced-by-count":3,"title":["Disease Monitoring in Inflammatory Bowel Disease Daily Clinical Practice and Impact on Treatment Decision Making: Real World Evidence From the Inflammatory Bowel Disease\u2010PODCAST Study"],"prefix":"10.1002","volume":"13","author":[{"given":"Axel","family":"Dignass","sequence":"first","affiliation":[{"name":"Department of Medicine I Agaplesion Markus Hospital Goethe University  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Magro","sequence":"additional","affiliation":[{"name":"CINTESIS@RISE Department Faculdade de Medicina da Universidade do Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferdinando","family":"D\u2019Amico","sequence":"additional","affiliation":[{"name":"Gastroenterology and Endoscopy IRCCS Ospedale San Raffaele  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5492-5717","authenticated-orcid":false,"given":"Giorgos","family":"Bamias","sequence":"additional","affiliation":[{"name":"GI\u2010Unit 3rd Academic Department of Internal Medicine Sotiria Hospital National &amp; Kapodistrian University of Athens  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio Andrea","family":"Caprioli","sequence":"additional","affiliation":[{"name":"Gastroenterology and Endoscopy Unit Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico  Milan Italy"},{"name":"Department of Pathophysiology and Transplantation University of Milan  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Franchimont","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Erasme Hospital (ULB)  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ailsa","family":"Hart","sequence":"additional","affiliation":[{"name":"IBD Unit St Mark's Hospital and Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Koch","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, Gastroenterology, Hepatology &amp; Endocrinology Medical University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Koutroubakis","sequence":"additional","affiliation":[{"name":"Gastroenterology University Hospital of Heraklion Medical School University of Crete  Heraklion Crete Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse","family":"Siffledeen","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Covenant Health Grey Nuns Community Hospital  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Toruner","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ankara University School of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6081-508X","authenticated-orcid":false,"given":"Claudia","family":"Leitner","sequence":"additional","affiliation":[{"name":"AbbVie Inc.  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