{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:55:20Z","timestamp":1786978520015,"version":"build-2736575974"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["UEG Journal"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Endoscopic ultrasound\u2010guided portal pressure gradient (EUS\u2010PPG) measurement is a promising alternative to hepatic venous pressure gradient (HVPG) assessment, especially in settings where HVPG is unavailable or limited. The commercial 25\u2010gauge (25G) system showed good correlation with the hepatic venous pressure gradient (HVPG). However, the 25G has drawbacks due to its small caliber and the proprietary pressure transducer. The aim of this study was to validate a custom\u2010built 22G conventional intravascular pressure transducer system (22G EUS\u2010PPG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this prospective cohort study, 26 patients underwent EUS\u2010PPG measurement using both systems during the same session. The primary outcome was the correlation of PPG values. Secondary outcomes included the correlation and variability of portal vein pressure (PVP) and hepatic vein pressure (HVP) measured by both systems.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      PPG values showed excellent correlation of both systems (\n                      <jats:italic>r<\/jats:italic>\n                      \u00a0=\u00a00.901,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). 25G EUS\u2010PPG correctly identified clinically significant portal hypertension (CSPH, defined as PPG \u2265\u00a010mmHg) in 25 of 26 (96.2%) cases. Portal vein and hepatic vein pressures also correlated significantly (\n                      <jats:italic>r<\/jats:italic>\n                      \u00a0=\u00a00.776 and\n                      <jats:italic>r<\/jats:italic>\n                      \u00a0=\u00a00.673, respectively) between both systems. Variability within both systems was very low to low.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>EUS\u2010PPG measurements obtained using the commercial 25G and custom\u2010built 22G EUS\u2010PPG systems were validated. The custom\u2010built 22G system excels due to pressure\u2010tracing based quality control, availability and cost\u2010efficiency.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ueg2.70194","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:29:56Z","timestamp":1773012596000},"source":"Crossref","is-referenced-by-count":1,"title":["Same Session Validation of a Custom\u2010Built 22G With the Commercial 25G System for EUS\u2010Guided Portal Pressure Gradient Measurement"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7033-9956","authenticated-orcid":false,"given":"Michael","family":"Praktiknjo","sequence":"first","affiliation":[{"name":"Department of Medicine B University Hospital M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Farouk","sequence":"additional","affiliation":[{"name":"Department of Medicine B University Hospital M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Medicine B University Hospital M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Stadtmann","sequence":"additional","affiliation":[{"name":"Department of Medicine B University Hospital M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominik","family":"van de Loo","sequence":"additional","affiliation":[{"name":"Department of Medicine B University Hospital M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Kimmann","sequence":"additional","affiliation":[{"name":"Department of Medicine B University Hospital M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina","family":"Gunia","sequence":"additional","affiliation":[{"name":"Department of Medicine B University Hospital M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8748-651X","authenticated-orcid":false,"given":"J\u00f6rn Arne","family":"Meier","sequence":"additional","affiliation":[{"name":"Department of Medicine B University Hospital M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank Erhard","family":"Uschner","sequence":"additional","affiliation":[{"name":"Department of Medicine B University Hospital M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai\u2010Henrik","family":"Peiffer","sequence":"additional","affiliation":[{"name":"Department of Medicine B University Hospital M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wim","family":"Laleman","sequence":"additional","affiliation":[{"name":"Department of Medicine B University Hospital M\u00fcnster  M\u00fcnster Germany"},{"name":"Department of Gastroenterology and Hepatology Section of Liver and Biliopancreatic Disorders and Liver Transplantation University Hospitals Leuven KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7028-3881","authenticated-orcid":false,"given":"Jonel","family":"Trebicka","sequence":"additional","affiliation":[{"name":"Department of Medicine B University Hospital M\u00fcnster  M\u00fcnster Germany"},{"name":"European Foundation for the Study of Chronic Liver Failure  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Braden","sequence":"additional","affiliation":[{"name":"Department of Medicine B University Hospital M\u00fcnster  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