{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:56:38Z","timestamp":1786978598228,"version":"build-2736575974"},"reference-count":42,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,3,12]],"date-time":"2012-03-12T00:00:00Z","timestamp":1331510400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Most studies during pregnancy have assessed maternal left ventricular (LV) function by load\u2010dependent indices, assessing only chamber function. The aim of this study was to assess afterload\u2010adjusted LV myocardial and chamber systolic function at 24 weeks' gestation and 6 months postpartum in high\u2010risk normotensive pregnant women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A group of 118 high\u2010risk women with bilateral notching of the uterine arteries underwent an echocardiographic examination to evaluate midwall mechanics (midwall shortening (mFS%) and stress\u2010corrected midwall shortening (SCmFS%)) of the LV at 24 weeks' gestation and 6 months postpartum. Patients were followed until delivery and pregnancies were classified retrospectively as uneventful (uncomplicated outcome) or complicated. A control group of 54 low\u2010risk women with uneventful pregnancies without bilateral notching was also enrolled.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The pregnancy was uneventful in 74 (62.7%) women, whereas 44 (37.3%) developed complications. At 24 weeks' gestation, mFS% and SCmFS% were greater in the uncomplicated\u2010outcome compared with the complicated\u2010outcome group (25.9 \u00b1 4.8 vs 18.8 \u00b1 5.0%,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001 and 107.9 \u00b1 18.4 vs 77.9 \u00b1 20.7%,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001, respectively). At 6 months postpartum, SCmFS% remained greater in the uncomplicated\u2010outcome compared with the complicated\u2010outcome group (100.4 \u00b1 21.6 vs 87.8 \u00b1 19.1,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05). In the uncomplicated\u2010outcome group, SCmFS% was higher during pregnancy than it was postpartum, whereas in the complicated\u2010outcome group, it was lower during pregnancy than it was postpartum (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Maternal cardiac midwall mechanics appear to be enhanced (SCmFS% increased compared with controls) during pregnancy compared with postpartum in high\u2010risk patients with uncomplicated pregnancy, whereas midwall mechanics are depressed both during pregnancy and postpartum in patients with pregnancy complications. Copyright \u00a9 2012 ISUOG. Published by John Wiley &amp; Sons, Ltd.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/uog.10089","type":"journal-article","created":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T01:10:04Z","timestamp":1314839404000},"page":"430-437","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Left ventricular midwall mechanics at 24 weeks' gestation in high\u2010risk normotensive pregnant women: relationship to placenta\u2010related complications of pregnancy"],"prefix":"10.1002","volume":"39","author":[{"given":"G. P.","family":"Novelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Vasapollo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Gagliardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. M.","family":"Tiralongo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Pisani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Manfellotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Giannini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Valensise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,3,12]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1996.07030182.x"},{"key":"e_1_2_5_3_2","first-page":"378","article-title":"Uterine artery Doppler flow velocity waveforms in the second trimester for the prediction of preeclampsia and fetal growth retardation","volume":"83","author":"North RA","year":"1994","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1995.14.5.343"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1997.09050330.x"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1993.03010018.x"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1998.12050339.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(00)00946-7"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0960-7692.2001.00572.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1515\/JPM.2002.060"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.932"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2000.00192.x"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-002-0361-0"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.37.5.1209"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000058001.67791.0A"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.105858"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)90390-5"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.89.1.122"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)80201-X"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00153-Q"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.30.4.777"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5231"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(88)90090-7"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a136192"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1095"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2006.01013.x"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2004.03625.x"},{"key":"e_1_2_5_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(86)90224-9"},{"key":"e_1_2_5_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90385-Z"},{"key":"e_1_2_5_30_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.36.5.755"},{"key":"e_1_2_5_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)90390-5"},{"key":"e_1_2_5_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)00540-7"},{"key":"e_1_2_5_33_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.2.259"},{"key":"e_1_2_5_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(03)00475-7"},{"key":"e_1_2_5_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(01)01747-1"},{"key":"e_1_2_5_36_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000021601.49664.2A"},{"key":"e_1_2_5_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.euje.2005.07.007"},{"key":"e_1_2_5_38_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.31.4.929"},{"key":"e_1_2_5_39_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02780.x"},{"key":"e_1_2_5_40_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.127068"},{"key":"e_1_2_5_41_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2010.01120.x"},{"key":"e_1_2_5_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(98)00558-X"},{"key":"e_1_2_5_43_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.38.3.424"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.10089","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.10089","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.10089","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T21:05:34Z","timestamp":1698613534000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.10089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,12]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["10.1002\/uog.10089"],"URL":"https:\/\/doi.org\/10.1002\/uog.10089","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,12]]},"assertion":[{"value":"2011-08-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-03-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}