{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:09:18Z","timestamp":1791306558844,"version":"4.3.1"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,1,9]],"date-time":"2012-01-09T00:00:00Z","timestamp":1326067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe a new ultrasound technique that may be useful for the diagnosis of micrognathia in the first trimester of pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The retronasal triangle (RNT) view is a technique that captures the coronal plane of the face in which the primary palate and the frontal processes of the maxilla are visualized simultaneously. Normal first\u2010trimester fetuses display a characteristic gap between the right and left body of the mandible in this view (the \u2018mandibular gap\u2019). The presence or absence of this gap was evaluated and measured prospectively during real\u2010time scanning (<jats:italic>n<\/jats:italic> = 154) and retrospectively by analyzing three\u2010dimensional (3D) datasets (<jats:italic>n<\/jats:italic> = 50) in normal first\u2010trimester fetuses undergoing screening for aneuploidy at 11\u201313 weeks' gestation. 3D datasets from 12 fetuses with suspected micrognathia were also collected and examined retrospectively for the same features.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mandibular gap was identified in all 204 normal fetuses and increased linearly with increasing crown\u2013rump length (y = 0.033x + 0.435; <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> = 0.316), with no statistically significant differences between measurements obtained by two\u2010dimensional ultrasound and 3D offline analysis. Among fetuses with suspected micrognathia, three 3D datasets were excluded from analysis because of poor image quality in one and the diagnosis of a normal chin in two. In the remaining nine fetuses, the mandibular gap was absent and was replaced by a bony structure representing the receding chin in seven (77.8%) cases and was not visualized due to severe retrognathia in the remaining two (22.2%) cases. All fetuses with micrognathia had associated anomalies, including seven with aneuploidy and two with skeletal dysplasia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The RNT view may be a helpful technique for detecting micrognathia in the first trimester. The absence of the mandibular gap or failure to identify the mandible in this view is highly suggestive of micrognathia and should prompt a targeted ultrasound scan to assess for other anomalies. Further research is needed to determine the false\u2010positive and false\u2010negative rates of this technique. Copyright \u00a9 2012 ISUOG. Published by John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.10121","type":"journal-article","created":{"date-parts":[[2011,10,18]],"date-time":"2011-10-18T14:25:50Z","timestamp":1318947950000},"page":"152-156","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Absent mandibular gap in the retronasal triangle view: a clue to the diagnosis of micrognathia in the first trimester"],"prefix":"10.1002","volume":"39","author":[{"given":"W.","family":"Sepulveda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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