{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T10:47:43Z","timestamp":1763808463175},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,6,25]],"date-time":"2004-06-25T00:00:00Z","timestamp":1088121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2004,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the feasibility of sonographic depiction of the fetal hard palate and secondarily to create nomograms throughout gestation of its sonographic width, length and area.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a cross\u2010sectional study of pregnant patients between 15 and 41 weeks' gestation. Inclusion criteria consisted of well\u2010established dates (confirmed by early ultrasound), and singleton, non\u2010anomalous fetuses. Sonographic measurements obtained included biparietal diameter, head circumference, abdominal circumference and femur length. Fetal hard palate measurements included maximum width, maximum length and the calculated area. Tables were prepared depicting the estimated mean \u00b1 SD and 5<jats:sup>th<\/jats:sup>, 50<jats:sup>th<\/jats:sup> and 95<jats:sup>th<\/jats:sup> centiles at each gestational week between 15 and 41 weeks. Pearson's correlation coefficient and associated P\u2010values for the relationships between fetal hard palate measurements and other sonographic measurements and coefficients of variation for each of the fetal hard palate measurements were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included 602 consecutive patients. The mean maternal age was 28.7 \u00b1 6.3 years, with median gravidity of 2 (range, 1\u201312) and parity 1 (range, 0\u20138). All attempts at obtaining fetal hard palate ultrasound measurements were successful. Mean fetal hard palate width (cm) = \u22120.73579345 + 0.11370432 \u00d7 GA \u2212 0.00083919 \u00d7 GA<jats:sup>2<\/jats:sup> and SD = \u22120.017842055 + 0.005142475 \u00d7 GA, where GA is gestational age in weeks. Mean fetal hard palate length (cm) = \u22120.82020463 + 0.11767777 \u00d7 GA \u2212 0.00092801 \u00d7 GA<jats:sup>2<\/jats:sup> and SD = \u22120.043064317 + 0.006378869 \u00d7 GA. Mean fetal hard palate area (cm<jats:sup>2<\/jats:sup>) = \u22122.40090641 + 0.17136556 \u00d7 GA + 0.00097308 \u00d7 GA<jats:sup>2<\/jats:sup> and SD = \u22120.603647741 + 0.040740282 \u00d7 GA. Sonographic measurements of the fetal hard palate width, length and area correlated significantly and strongly with gestational age (all <jats:italic>P<\/jats:italic> &lt; 0.001) and significantly but less strongly with femur length (<jats:italic>P<\/jats:italic> = 0.004).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The fetal hard palate may be depicted sonographically with relative ease between 15 and 41 weeks' gestation and measurements of the fetal hard palate width, length and area correlate well with gestational age, biparietal diameter, abdominal circumference, sonographic estimated fetal weight, and femur length. Copyright \u00a9 2004 ISUOG. Published by John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.1063","type":"journal-article","created":{"date-parts":[[2004,6,25]],"date-time":"2004-06-25T11:01:03Z","timestamp":1088161263000},"page":"35-41","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Nomograms of sonographic measurements throughout gestation of the fetal hard palate width, length and area"],"prefix":"10.1002","volume":"24","author":[{"given":"D. M.","family":"Sherer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sokolovski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. G.","family":"Santoso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Dalloul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Abulafia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,6,25]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1992.tb03225.x"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198111000-00031"},{"key":"e_1_2_5_4_2","first-page":"199","volume-title":"Fetology: diagnosis and management of the fetal patient","author":"Bianchi DW","year":"2000"},{"key":"e_1_2_5_5_2","first-page":"16","article-title":"Etiology of facial clefts: prospective evaluation of 428 patients","volume":"25","author":"Jones MC","year":"1988","journal-title":"Cleft Palate J"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(2000)037<0041:AMICWO>2.3.CO;2"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1086\/302498"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0960-7692.2001.00575.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(2002)039<0169:PDOCLA>2.0.CO;2"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-3995(00)00011-3"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000053908"},{"key":"e_1_2_5_12_2","first-page":"268","volume-title":"Gray's Anatomy","author":"Williams PL","year":"1997"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2001.20.11.1165"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0960-7692.2001.00508.x"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0223(200011)20:11<870::AID-PD940>3.0.CO;2-J"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970131009"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-5629(01)00403-3"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2000.00181.x"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.127127"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2002.00773.x"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.217.1.r00oc18236"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2000.00323.x"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2002.00721.x"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.918"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1999.14050333.x"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.1063","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.1063","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.1063","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T16:41:43Z","timestamp":1696783303000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.1063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6,25]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,7]]}},"alternative-id":["10.1002\/uog.1063"],"URL":"https:\/\/doi.org\/10.1002\/uog.1063","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,6,25]]},"assertion":[{"value":"2004-02-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2004-06-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}