{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:00:23Z","timestamp":1790960423085,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,3,4]],"date-time":"2013-03-04T00:00:00Z","timestamp":1362355200000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet & Gyne"],"published-print":{"date-parts":[[2013,3]]},"abstract":"ABSTRACT<\/jats:title>Objective<\/jats:title>To evaluate the feasibility of transvaginal hysterosalpingo\u2010contrast sonography (HyCoSy<\/jats:styled-content>) with new automated three\u2010dimensional coded contrast imaging (3D\u2010CCI<\/jats:styled-content>) software in the evaluation of tubal patency and visualization of tubal course.<\/jats:p><\/jats:sec>Methods<\/jats:title>Patients undergoing HyCoSy<\/jats:styled-content> with automated 3D\u2010CCI<\/jats:styled-content> software were evaluated prospectively. First, to evaluate the feasibility of 3D<\/jats:styled-content> visualization of tubal course, we performed consecutive volume acquisitions while injecting SonoVue<\/jats:styled-content> contrast agent. We then performed conventional two\u2010dimensional (2D<\/jats:styled-content>) real\u2010time HyCoSy<\/jats:styled-content> to confirm tubal patency status by detection of saline and air bubbles moving through the Fallopian tubes and around the ovaries. We also evaluated visualization with CCI<\/jats:styled-content> of the contrast agent around the ovaries, side effects and pain during and after the procedure, by visual analog scale (VAS<\/jats:styled-content>) (ranging from 0 to 10, with 0 corresponding to no pain and 10 corresponding to maximum pain).<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 126 patients (252 tubes) underwent 3D\u2010CCI HyCoSy<\/jats:styled-content> followed by 2D<\/jats:styled-content> real\u2010time HyCoSy<\/jats:styled-content>. According to the final 2D<\/jats:styled-content> real\u2010time evaluation, bilateral tubal patency was observed in 111 patients, bilateral tubal occlusion in four patients and unilateral tubal patency in 11 patients. The concordance rate for tubal patency status between the first 3D<\/jats:styled-content> volume acquisition and the final 2D<\/jats:styled-content> real\u2010time evaluation was 84% and that between the second 3D<\/jats:styled-content> volume acquisition and the final 2D<\/jats:styled-content> real\u2010time evaluation was 97%. A pain score >5 on VAS<\/jats:styled-content> was recorded in 58% of patients during the procedure, but a pain score \u2264\u20095 was recorded in 85.7% of patients immediately after the procedure.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>HyCoSy<\/jats:styled-content> with automated 3D\u2010CCI<\/jats:styled-content> technology retains the advantages of conventional 2D HyCoSy<\/jats:styled-content> while overcoming the disadvantages. 2D HyCoSy<\/jats:styled-content> is highly observer\u2010dependent and is only accurate in the hands of experienced investigators; by obtaining a volume of the uterus and tubes, automated 3D<\/jats:styled-content> volume acquisition permits visualization of the tubes in the coronal view and of the tubal course in 3D<\/jats:styled-content> space, and should allow less experienced operators to evaluate tubal patency status relatively easily. Copyright \u00a9 2012 ISUOG. Published by John Wiley & Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.11200","type":"journal-article","created":{"date-parts":[[2012,5,30]],"date-time":"2012-05-30T16:02:32Z","timestamp":1338393752000},"page":"328-335","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Automated three\u2010dimensional coded contrast imaging hysterosalpingo\u2010contrast sonography: feasibility in office tubal patency testing"],"prefix":"10.1002","volume":"41","author":[{"given":"C.","family":"Exacoustos","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Universit\u00e0 degli Studi di Roma \u2018Tor Vergata\u2019 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Di Giovanni","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Universit\u00e0 degli Studi di Roma \u2018Tor Vergata\u2019 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Szabolcs","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Universit\u00e0 degli Studi di Roma \u2018Tor Vergata\u2019 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Romeo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Universit\u00e0 degli Studi di Roma \u2018Tor Vergata\u2019 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. E.","family":"Romanini","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Universit\u00e0 degli Studi di Roma \u2018Tor Vergata\u2019 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Luciano","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Center for Fertility and Women's Health University of Connecticut School of Medicine New Britain CT USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Zupi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Universit\u00e0 degli Studi di Roma \u2018Tor Vergata\u2019 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Arduini","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Universit\u00e0 degli Studi di Roma \u2018Tor Vergata\u2019 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,3,4]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2002.00784.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/der046"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/16.12.2481"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-3804(05)60264-2"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1996.07010043.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.07.1777"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1999.14030205.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2002.00823.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0096(199611\/12)24:9<523::AID-JCU6>3.0.CO;2-P"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2262011450"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2004.23.12.1629"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2005.24.9.1267"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4013"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2008.27.7.1011"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7464"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2007.07.008"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2009.03.019"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.07.1746"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.08.065"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7442"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.11085"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2010.07.018"}],"container-title":["Ultrasound in Obstetrics & Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.11200","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.11200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T20:38:31Z","timestamp":1692563911000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.11200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1002\/uog.11200"],"URL":"https:\/\/doi.org\/10.1002\/uog.11200","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3]]},"assertion":[{"value":"2012-04-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-03-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}