{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:36:21Z","timestamp":1762101381986},"reference-count":37,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,3,25]],"date-time":"2013-03-25T00:00:00Z","timestamp":1364169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To examine the relationship between prenatal umbilical artery (<jats:styled-content style=\"fixed-case\">UA<\/jats:styled-content>) and internal carotid artery (<jats:styled-content style=\"fixed-case\">ICA<\/jats:styled-content>) Doppler findings and cognitive development at 3 and 6 years in low\u2010birth\u2010weight children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a study of 209 low\u2010birth\u2010weight (&lt;\u200910<jats:sup>th<\/jats:sup> centile) children born after 28 gestational weeks with <jats:styled-content style=\"fixed-case\">UA<\/jats:styled-content> resistance index (RI) measured within 2 weeks before delivery. Children with normal <jats:styled-content style=\"fixed-case\">UA<\/jats:styled-content>\u2010 and <jats:styled-content style=\"fixed-case\">ICA\u2010RI<\/jats:styled-content> were defined as small\u2010for\u2010gestational age (<jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>) and those with abnormal <jats:styled-content style=\"fixed-case\">UA<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">ICA<\/jats:styled-content> Doppler findings as having fetal growth restriction (<jats:styled-content style=\"fixed-case\">FGR<\/jats:styled-content>). Cognitive ability at 3 and 6 years' corrected age was assessed using the fourth edition of the Stanford\u2013Binet Intelligence Scale (<jats:styled-content style=\"fixed-case\">SBIS<\/jats:styled-content>) and compared between <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">FGR<\/jats:styled-content> groups. An <jats:styled-content style=\"fixed-case\">SBIS<\/jats:styled-content> score &lt;\u200985 was considered to indicate delayed development.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median gestational age at diagnosis of abnormal fetal growth was 36.6 (range, 28\u201341) weeks. There were 87 (41.6%) children classified as having <jats:styled-content style=\"fixed-case\">FGR<\/jats:styled-content> and 122 (58.4%) as <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>. The mean global <jats:styled-content style=\"fixed-case\">SBIS<\/jats:styled-content> score at 3 years was 109.4 (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>, 22.8) and at 6 years it was 110.5 (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>, 13.9). Overall, 22 (10.5%) children had delayed development at 3 years. Total <jats:styled-content style=\"fixed-case\">SBIS<\/jats:styled-content> scores and individual domain scores did not differ between <jats:styled-content style=\"fixed-case\">FGR<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> groups at 3 or 6 years and similar proportions in each group had delayed development.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Abnormal prenatal <jats:styled-content style=\"fixed-case\">UA<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">ICA<\/jats:styled-content> Doppler findings are not associated with lower developmental scores in low\u2010birth\u2010weight children delivered in the third trimester of pregnancy. Copyright \u00a9 2013 ISUOG. 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