{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:13:13Z","timestamp":1772118793291,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,9,23]],"date-time":"2013-09-23T00:00:00Z","timestamp":1379894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet & Gyne"],"published-print":{"date-parts":[[2013,10]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objective<\/jats:title>\n \n Transvaginal sonography (\n TVS<\/jats:styled-content>\n ) is core to any ovarian cancer screening strategy. General\u2010population screening involves older postmenopausal women in whom ovarian visualization is difficult because of decreasing ovarian size and lack of follicular activity. We report on factors affecting the visualization of postmenopausal ovaries in the multicenter United Kingdom Collaborative Trial of Ovarian Cancer Screening (\n UKCTOCS<\/jats:styled-content>\n ).\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n The\n UKCTOCS<\/jats:styled-content>\n is a randomized controlled trial of 202 638 postmenopausal women with 50 639 women in the ultrasound scan arm. TVS is the primary screening modality in the ultrasound scan arm. Age, education, ethnicity, body mass index (\n BMI<\/jats:styled-content>\n ), previous pelvic surgery, lifestyle and reproductive factors, and a personal\/family history of cancer were assessed for their effects on ovarian visualization at the initial\n TVS<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Between 11 June 2001 and 18 August 2007, 43 867 women underwent\n TVS<\/jats:styled-content>\n . The median age and\n BMI<\/jats:styled-content>\n of the women were 60.6 (interquartile range (\n IQR<\/jats:styled-content>\n ), 9.9) years and 25.7 (\n IQR<\/jats:styled-content>\n , 5.8), respectively. The right ovary was visualized in 29 297 (66.8%) and the left ovary was visualized in 28 726 (65.5%). Visualization of ovaries decreased with previous hysterectomy (odds ratio (\n OR<\/jats:styled-content>\n ) = 0.534; 95%\n CI<\/jats:styled-content>\n , 0.504\u20130.567), previous tubal ligation (\n OR<\/jats:styled-content>\n = 0.895; 95%\n CI<\/jats:styled-content>\n , 0.852\u20130.940), increasing age (\n OR<\/jats:styled-content>\n = 0.953; 95%\n CI<\/jats:styled-content>\n , 0.950\u20130.956), unilateral oophorectomy (\n OR<\/jats:styled-content>\n = 0.224; 95%\n CI<\/jats:styled-content>\n , 0.186\u20130.269) and being overweight (\n OR<\/jats:styled-content>\n = 0.918; 95%\n CI<\/jats:styled-content>\n , 0.876\u20130.962) or obese (\n OR<\/jats:styled-content>\n = 0.715; 95%\n CI<\/jats:styled-content>\n , 0.677\u20130.755). Increased visualization was observed with a history of infertility (\n OR<\/jats:styled-content>\n = 1.134; 95%\n CI<\/jats:styled-content>\n , 1.005\u20131.279) and increasing age (in years) at menopause (\n OR<\/jats:styled-content>\n = 1.005; 95%\n CI<\/jats:styled-content>\n , 1.001\u20131.009).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Several factors affect the visualization of postmenopausal ovaries. Their impact needs to be taken into consideration when developing quality assurance for ovarian ultrasound scanning or comparing study results as their prevalence may differ between populations. Copyright \u00a9 2013 ISUOG. Published by John Wiley & Sons Ltd.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/uog.12447","type":"journal-article","created":{"date-parts":[[2013,3,2]],"date-time":"2013-03-02T02:17:32Z","timestamp":1362190652000},"page":"472-477","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Factors affecting visualization of postmenopausal ovaries: descriptive study from the multicenter United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)"],"prefix":"10.1002","volume":"42","author":[{"given":"A.","family":"Sharma","sequence":"first","affiliation":[{"name":"Women's Cancer UCL EGA Institute for Women's Health London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Burnell","sequence":"additional","affiliation":[{"name":"Women's Cancer UCL EGA Institute for Women's Health London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Gentry\u2010Maharaj","sequence":"additional","affiliation":[{"name":"Women's Cancer UCL EGA Institute for Women's Health London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Campbell","sequence":"additional","affiliation":[{"name":"Create Health Clinic London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. N.","family":"Amso","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, School of Medicine Cardiff University Cardiff UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. W.","family":"Seif","sequence":"additional","affiliation":[{"name":"Academic Unit of Obstetrics and Gynaecology St Mary's Hospital Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Fletcher","sequence":"additional","affiliation":[{"name":"Women's Cancer UCL EGA Institute for Women's Health London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Brunel","sequence":"additional","affiliation":[{"name":"Department of Radiology University College London Hospitals London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Turner","sequence":"additional","affiliation":[{"name":"Department of Radiology Royal Derby Hospital Derby UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Rangar","sequence":"additional","affiliation":[{"name":"Northern Gynaecological Oncology Centre Queen Elizabeth Hospital Gateshead UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ryan","sequence":"additional","affiliation":[{"name":"Women's Cancer UCL EGA Institute for Women's Health London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Women's Cancer UCL EGA Institute for Women's Health London UK"},{"name":"Faculty of Medical and Human Sciences, University of Manchester Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Menon","sequence":"additional","affiliation":[{"name":"Women's Cancer UCL EGA Institute for Women's Health London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(09)70026-9"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2000.5816"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-2456(00)00098-2"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2007.01035.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/gme.0b013e31816ddb6f"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/gme.0b013e3181aa1c93"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-05-0847"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.107401"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a2079"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1999.13010011.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00696.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.159.1.3952295"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.06.0409"}],"container-title":["Ultrasound in Obstetrics & Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.12447","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.12447","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T15:43:50Z","timestamp":1696347830000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.12447"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,23]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1002\/uog.12447"],"URL":"https:\/\/doi.org\/10.1002\/uog.12447","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717995298.793475812","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.717995298.793475424","asserted-by":"object"}]},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,23]]},"assertion":[{"value":"2012-04-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-02-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-09-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}