{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T20:32:53Z","timestamp":1776457973080,"version":"3.51.2"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,3,4]],"date-time":"2014-03-04T00:00:00Z","timestamp":1393891200000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p><jats:italic>To evaluate the role of cervical length (<jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content>) and uterine artery pulsatility index (<jats:styled-content style=\"fixed-case\">UtA\u2010PI<\/jats:styled-content>) at 11\u2009+\u20090 to 13\u2009+\u20096\u2009weeks as predictors of spontaneous preterm delivery (<jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content>) in a Chilean population<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:italic>This was a prospective study of asymptomatic women with singleton pregnancies attending for a nuchal translucency scan at 11\u2009+\u20090 to 13\u2009+\u20096\u2009weeks' gestation and who underwent a transvaginal scan for evaluation of <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">UtA\u2010PI<\/jats:styled-content>. Exclusion criteria were fetal and pregnancy complications (other than <jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content>) and iatrogenic delivery at\u2009&lt;\u200934\u2009weeks. Measurements of <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">UtA\u2010PI<\/jats:styled-content> were adjusted for fetal crown\u2013rump length and maternal characteristics and expressed as multiples of the median (<jats:styled-content style=\"fixed-case\">MoM<\/jats:styled-content>) of the unaffected group. Prediction of <jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content> using maternal and pregnancy characteristics was studied using logistic regression analysis<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:italic>A total of 3480 women were recruited into the study and, after application of exclusion criteria, 3310 were included in the analysis. The rate of <jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content> at\u2009&lt;\u200934\u2009weeks was 0.9% (<\/jats:italic>n\u2009=\u2009<jats:italic>31). A previous <jats:styled-content style=\"fixed-case\">PTD<\/jats:styled-content> had occurred in 7.4% of parous women. Patients with <jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content> in the index pregnancy were characterized by a significantly higher prevalence of previous <jats:styled-content style=\"fixed-case\">PTD<\/jats:styled-content> (12.9%<\/jats:italic> vs <jats:italic>3.7%<\/jats:italic>, P\u2009&lt;\u2009<jats:italic>0.05). No significant difference was found in either <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">UtA\u2010PI<\/jats:styled-content> between pregnancies with and without subsequent <jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content>. Logistic regression analysis showed that smoking and previous <jats:styled-content style=\"fixed-case\">PTD<\/jats:styled-content> were significantly associated with <jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content> at\u2009&lt;\u200934\u2009weeks. The combination of these characteristics provided a detection rate of 26% with a false\u2010positive rate of 8%<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:italic>Neither <jats:styled-content style=\"fixed-case\">UtA\u2010PI<\/jats:styled-content> nor <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> during the first trimester was shown to be a useful predictor of early <jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content>. However, a combined model that includes smoking and previous <jats:styled-content style=\"fixed-case\">PTD<\/jats:styled-content> predicts approximately one\u2010quarter of those women destined to deliver at\u2009&lt;\u200934\u2009weeks, with a false\u2010positive rate of 8%. Copyright \u00a9 2013 ISUOG. Published by John Wiley &amp; Sons Ltd<\/jats:italic><\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.12465","type":"journal-article","created":{"date-parts":[[2013,3,22]],"date-time":"2013-03-22T14:06:51Z","timestamp":1363961211000},"page":"291-296","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Is there a role for cervical assessment and uterine artery Doppler in the first trimester of pregnancy as a screening test for spontaneous preterm delivery?"],"prefix":"10.1002","volume":"43","author":[{"given":"M.","family":"Parra\u2010Cordero","sequence":"first","affiliation":[{"name":"Fetal Medicine Unit University of Chile Hospital Santiago Chile"},{"name":"Fetal Medicine Unit Hospital San Borja Arriar\u00e1n Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Sep\u00falveda\u2010Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit University of Chile Hospital Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Rencoret","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit Hospital San Borja Arriar\u00e1n Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Vald\u00e9s","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit University of Chile Hospital Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Pedraza","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit University of Chile Hospital Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit University of Chile Hospital Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,4]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198501103120204"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.11.001"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5333"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000335686"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2011.30.7.997"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2006.03.021"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2010.501124"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000341712"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.02.109"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12264"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.127720"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0002-9378(03)00838-X"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.2594"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh106"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.3919"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2662"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2640"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7439"},{"key":"e_1_2_6_20_1","volume-title":"Sample Size And Power: Comparisons And Estimations For Independent Proportions, Means, Correlations, Risks And Rates","author":"Domenech JM","year":"2012"},{"key":"e_1_2_6_21_1","unstructured":"DawsonB TrappR. 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