{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T18:35:32Z","timestamp":1785522932101,"version":"3.56.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,1,7]],"date-time":"2014-01-07T00:00:00Z","timestamp":1389052800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2014,1,7]],"date-time":"2014-01-07T00:00:00Z","timestamp":1389052800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      <jats:italic>\n                        To construct nomograms of the dimensions of the fetal posterior fossa (\n                        <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>\n                        ), assessed in the mid\u2010sagittal plane in the second and third trimesters, and to assess how measurements from fetuses with\n                        <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>\n                        abnormalities deviate from our normal ranges\n                      <\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      <jats:italic>\n                        This was a prospective cross\u2010sectional study of 378 healthy fetuses in low\u2010risk singleton pregnancies between 15 and 35\u2009weeks.\n                        <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>\n                        size was evaluated in the mid\u2010sagittal plane of the fetal head using three\u2010dimensional multiplanar reconstruction (\n                        <jats:styled-content style=\"fixed-case\">3D\u2010MPR<\/jats:styled-content>\n                        ). The borders of the\n                        <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>\n                        were defined from the clivus to the tentorium (clivotentorial distance,\n                        <jats:styled-content style=\"fixed-case\">CTD<\/jats:styled-content>\n                        ) and from the occipital bone to the level of the upper mesencephalic edge (tecto\u2010occipital distance,\n                        <jats:styled-content style=\"fixed-case\">TOD<\/jats:styled-content>\n                        ), and the posterior fossa area (\n                        <jats:styled-content style=\"fixed-case\">PFA<\/jats:styled-content>\n                        ) and perimeter (\n                        <jats:styled-content style=\"fixed-case\">PFP<\/jats:styled-content>\n                        ) were assessed. Growth charts were produced. Thirty\u2010nine fetuses diagnosed with\n                        <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>\n                        malformations were analyzed by calculating the\n                      <\/jats:italic>\n                      z\u2010\n                      <jats:italic>\n                        scores of\n                        <jats:styled-content style=\"fixed-case\">PFA<\/jats:styled-content>\n                        ,\n                        <jats:styled-content style=\"fixed-case\">PFP<\/jats:styled-content>\n                        ,\n                        <jats:styled-content style=\"fixed-case\">TOD<\/jats:styled-content>\n                        and\n                        <jats:styled-content style=\"fixed-case\">CTD<\/jats:styled-content>\n                        , relative to the developed nomograms\n                      <\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:italic>\n                        Of the 378 healthy fetuses initially included, there were 281 with adequate visualization of the\n                        <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>\n                        borders; i.e.\n                        <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>\n                        mid\u2010sagittal plane morphometry was feasible in 74.3% of cases. There was a linear relationship between each of\n                        <jats:styled-content style=\"fixed-case\">PFA<\/jats:styled-content>\n                        ,\n                        <jats:styled-content style=\"fixed-case\">PFP<\/jats:styled-content>\n                        ,\n                        <jats:styled-content style=\"fixed-case\">TOD<\/jats:styled-content>\n                        and\n                        <jats:styled-content style=\"fixed-case\">CTD<\/jats:styled-content>\n                        , and gestational age, with Pearson correlation coefficients of 0.97, 0.97, 0.96 and 0.95, respectively (\n                      <\/jats:italic>\n                      P\u2009&lt;\u2009\n                      <jats:italic>\n                        0.001 for each). Chiari\n                        <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>\n                        malformation (\n                        <jats:styled-content style=\"fixed-case\">CM\u2010II<\/jats:styled-content>\n                        ) and Dandy\u2013Walker malformation (\n                        <jats:styled-content style=\"fixed-case\">DWM<\/jats:styled-content>\n                        ) were associated with the greatest difference in\n                        <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>\n                        size compared with normal;\n                        <jats:styled-content style=\"fixed-case\">PFA<\/jats:styled-content>\n                      <\/jats:italic>\n                      z\u2010\n                      <jats:italic>\n                        scores exceeded 2.6 in all five\n                        <jats:styled-content style=\"fixed-case\">DWM<\/jats:styled-content>\n                        cases and were below \u22122.66 in all 11\n                        <jats:styled-content style=\"fixed-case\">CM\u2010II<\/jats:styled-content>\n                        cases\n                      <\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      <jats:italic>\n                        Sonographic evaluation of fetal\n                        <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>\n                        size in the mid\u2010sagittal plane is feasible. Our constructed nomograms provide reference data that may be helpful when evaluating\n                        <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>\n                        congenital malformations. Copyright \u00a9 2013 ISUOG. Published by John Wiley &amp; Sons Ltd\n                      <\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/uog.12508","type":"journal-article","created":{"date-parts":[[2013,5,13]],"date-time":"2013-05-13T12:45:05Z","timestamp":1368449105000},"page":"147-153","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Fetal posterior fossa dimensions: normal and anomalous development assessed in mid\u2010sagittal cranial plane by three\u2010dimensional multiplanar sonography"],"prefix":"10.1002","volume":"43","author":[{"given":"Z.","family":"Leibovitz","sequence":"first","affiliation":[{"name":"Division of Prenatal Diagnosis, Department of Obstetrics and Gynecology Wolfson Medical Center Holon Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. 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