{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T15:57:57Z","timestamp":1790351877193,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,3,12]],"date-time":"2014-03-12T00:00:00Z","timestamp":1394582400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2014,4]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objectives<\/jats:title>\n \n To investigate fetal venous Doppler measurements in monochorionic twin pregnancies complicated by placental insufficiency and the relationship between fetal venous flow and acidemia at birth or intrauterine fetal death<\/jats:italic>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n \n This was a prospective study of 18 monochorionic twin pregnancies with placental insufficiency. Inclusion criteria were monochorionic\u2013diamniotic twin pregnancy, abnormal umbilical artery (\n UA<\/jats:styled-content>\n ) Doppler indices, intact membranes and absence of fetal congenital abnormalities. Cases of twin\u2010to\u2010twin transfusion syndrome were excluded. The following Doppler measurements were studied:\n UA<\/jats:styled-content>\n pulsatility index (\n PI<\/jats:styled-content>\n ), ductus venosus\n PI<\/jats:styled-content>\n , middle cerebral artery\n PI<\/jats:styled-content>\n and peak systolic velocity, intra\u2010abdominal umbilical vein (\n UV<\/jats:styled-content>\n ) time\u2010averaged maximum velocity (\n TAMXV<\/jats:styled-content>\n ) and left portal vein (\n LPV<\/jats:styled-content>\n )\n TAMXV<\/jats:styled-content>\n . Doppler parameters were transformed into\n <\/jats:italic>\n Z\u2010\n \n scores (\n SD<\/jats:styled-content>\n values from the mean) or multiples of the median according to normative references\n <\/jats:italic>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n \n UA pH<\/jats:styled-content>\n \u2009<\u20097.20 occurred in nine (25.0%) neonates,\n pH<\/jats:styled-content>\n \u2009<\u20097.15 in four (11.1%) and intrauterine death in four (11.1%) fetuses. The\n UV\u2010TAMXV<\/jats:styled-content>\n and\n LPV\u2010TAMXV<\/jats:styled-content>\n <\/jats:italic>\n Z\u2010\n \n scores were significantly lower in the group with\n pH<\/jats:styled-content>\n \u2009<\u20097.20 or intrauterine fetal death (\u20131.79\n <\/jats:italic>\n vs \u2013\n 1.22<\/jats:italic>\n , P\u2009=\u2009\n 0.006 and \u20132.26<\/jats:italic>\n vs \u2013\n 1.13<\/jats:italic>\n , P\u2009=\u2009\n \n 0.04, respectively). In cases with\n pH<\/jats:styled-content>\n \u2009<\u20097.15 or intrauterine fetal death,\n UV<\/jats:styled-content>\n pulsations were more frequent (50.0%\n <\/jats:italic>\n vs\n 10.7%<\/jats:italic>\n , P\u2009=\u2009\n \n 0.03) and\n UV\u2010TAMXV<\/jats:styled-content>\n <\/jats:italic>\n Z\u2010\n score was significantly lower (\u20131.89<\/jats:italic>\n vs \u2013\n 1.26<\/jats:italic>\n , P\u2009=\u2009\n \n 0.003). Mixed effects logistic regression analysis, accounting for the paired nature of the outcomes for the two twins in each pregnancy, demonstrated that the\n UV\u2010TAMXV<\/jats:styled-content>\n <\/jats:italic>\n Z\u2010\n \n score significantly predicted\n UA pH<\/jats:styled-content>\n at birth\u2009<\u20097.20 or intrauterine fetal death. The Doppler parameter that independently predicted\n pH<\/jats:styled-content>\n \u2009<\u20097.15 or intrauterine fetal death was presence of pulsation in the\n UV<\/jats:styled-content>\n <\/jats:italic>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n \n UV<\/jats:styled-content>\n Doppler parameters may predict acidemia at birth or intrauterine fetal death in monochorionic twins complicated by placental insufficiency. Copyright \u00a9 2013 ISUOG. Published by John Wiley & Sons Ltd\n <\/jats:italic>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/uog.12549","type":"journal-article","created":{"date-parts":[[2013,6,25]],"date-time":"2013-06-25T13:04:44Z","timestamp":1372165484000},"page":"426-431","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Fetal venous circulation in monochorionic twin pregnancies with placental insufficiency: prediction of acidemia at birth or intrauterine fetal death"],"prefix":"10.1002","volume":"43","author":[{"given":"T. B.","family":"Liao","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. M. Y.","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. W.","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. P .V.","family":"Francisco","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Zugaib","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,3,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1997.tb10948.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1105"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1986.tb07932.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.91.1.129"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1902"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2012.711394"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0960-7692.2001.00591.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.965"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2009.06.029"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2003.11.028"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpme.1990.18.3.165"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2012(05)08"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4046"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5146"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.902"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200001063420102"},{"key":"e_1_2_5_19_1","unstructured":"OomsJCL.yeroon.net\/lme4: A web interface for the R package lme4. Version 0.1. 2009.http:\/\/www.yeroon.net\/lme4."},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.78"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1994.04020109.x"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016340903214924"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.10.596"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.04.022"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1630"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1375\/twin.14.2.192"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1900"}],"container-title":["Ultrasound in Obstetrics & Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.12549","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.12549","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T00:02:24Z","timestamp":1696464144000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.12549"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,12]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1002\/uog.12549"],"URL":"https:\/\/doi.org\/10.1002\/uog.12549","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,12]]},"assertion":[{"value":"2012-10-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-06-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-03-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}