{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T13:14:18Z","timestamp":1791465258024,"version":"4.3.4"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,3,3]],"date-time":"2014-03-03T00:00:00Z","timestamp":1393804800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p><jats:italic>To estimate the association between antenatal bowel dilation and postnatal small\u2010bowel atresia in fetal gastroschisis and to establish a threshold at which the risk of adverse neonatal outcome increases<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:italic>This was a retrospective cohort study of singleton gestations with an antenatal diagnosis of gastroschisis seen in our ultrasound unit from 2001 to 2010. We reviewed stored images from the last ultrasound examination before delivery, blinded to postnatal diagnoses and outcomes. Fetal intra\u2010 and extra\u2010abdominal bowel dilation (<jats:styled-content style=\"fixed-case\">IABD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">EABD<\/jats:styled-content>, respectively) and bowel\u2010wall thickness were measured. Previously published definitions of bowel dilation, including &gt;\u20096, &gt;\u200910, &gt;\u200914 and\u2009&gt;\u200918\u2009mm, were evaluated for association with the primary outcome of bowel atresia. The optimal threshold to define fetal bowel dilation was determined by evaluating the significance of association as well as test performance characteristics<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:italic>Of 109 consecutive patients with fetal gastroschisis, there were four cases of intrauterine fetal demise and three neonatal deaths. Of the 94 live births with complete outcome data, 39 (41.5%) had measurable <jats:styled-content style=\"fixed-case\">IABD<\/jats:styled-content>. There were 14 (14.9%) cases of bowel atresia. Using a threshold of\u2009&gt;\u200914\u2009mm, <jats:styled-content style=\"fixed-case\">IABD<\/jats:styled-content> was significantly associated with an increased risk for bowel atresia (relative risk, 3.1 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 1.2\u20138.2)) with a sensitivity of 57.1%, specificity of 75.0%, positive predictive value of 28.6% and negative predictive value of 90.9%. <jats:styled-content style=\"fixed-case\">IABD<\/jats:styled-content> &gt;\u200914\u2009mm was also associated with a significantly longer stay in neonatal intensive care unit. There was no significant association between <jats:styled-content style=\"fixed-case\">EABD<\/jats:styled-content> and bowel atresia at any of the thresholds evaluated<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:italic><jats:styled-content style=\"fixed-case\">IABD<\/jats:styled-content> &gt;\u200914\u2009mm is associated with an increased risk for postnatal bowel atresia in fetal gastroschisis. This finding may be useful in counseling patients regarding the anticipated postnatal course for their neonate. Copyright \u00a9 2013 ISUOG. Published by John Wiley &amp; Sons Ltd<\/jats:italic>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.12568","type":"journal-article","created":{"date-parts":[[2013,7,25]],"date-time":"2013-07-25T18:46:40Z","timestamp":1374778000000},"page":"420-425","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Sonographic predictors of postnatal bowel atresia in fetal gastroschisis"],"prefix":"10.1002","volume":"43","author":[{"given":"K. R.","family":"Goetzinger","sequence":"first","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Washington University School of Medicine St Louis MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. G.","family":"Tuuli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Washington University School of Medicine St Louis MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. E.","family":"Longman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Washington University School of Medicine St Louis MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. M.","family":"Huster","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Washington University School of Medicine St Louis MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. O.","family":"Odibo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Washington University School of Medicine St Louis MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. G.","family":"Cahill","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Washington University School of Medicine St Louis MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,3,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.332.7536.250"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2153"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.332.7538.423-a"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000078990"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2001.20004"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211616"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.2858"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2011.03.033"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2011.11.022"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.10.888"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7514"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-009-2342-x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2008.140434"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1991.10.4.211"},{"key":"e_1_2_5_16_1","first-page":"53","article-title":"Prenatal diagnosis of gastroschisis: development of objective sonographic criteria for predicting outcome","volume":"81","author":"Langer JC","year":"1993","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2011.03183.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.09.016"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(88)80360-9"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.12568","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.12568","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T04:02:33Z","timestamp":1696478553000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.12568"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,3]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1002\/uog.12568"],"URL":"https:\/\/doi.org\/10.1002\/uog.12568","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,3]]},"assertion":[{"value":"2013-05-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-07-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-03-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}