{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T18:10:16Z","timestamp":1775326216467,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,4,15]],"date-time":"2014-04-15T00:00:00Z","timestamp":1397520000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet & Gyne"],"published-print":{"date-parts":[[2014,5]]},"abstract":"ABSTRACT<\/jats:title>Objectives<\/jats:title>To evaluate the association between second\u2010trimester uterine artery (UtA<\/jats:styled-content>) Doppler pulsatility index (PI<\/jats:styled-content>) with reduced fetal movements (RFM<\/jats:styled-content>) and adverse pregnancy outcome at term.<\/jats:p><\/jats:sec>Methods<\/jats:title>This was a retrospective cohort study of all singleton pregnancies referred for routine antenatal care at a fetal medicine unit over a 5\u2010year period. UtA<\/jats:styled-content> Doppler indices were obtained at the time of the routine anomaly scan between 19 and 23\u2009weeks' gestation to assess the risk for pre\u2010eclampsia. All episodes of RFM<\/jats:styled-content> within 1\u2009month of the expected date of delivery were recorded. Regression and sensitivity analyses were used to assess the relationship between UtA\u2010PI<\/jats:styled-content> with RFM<\/jats:styled-content>, small\u2010for\u2010gestational\u2010age (SGA<\/jats:styled-content>) fetuses and stillbirth after 36\u2009weeks' gestation.<\/jats:p><\/jats:sec>Results<\/jats:title>Overall, 17\u2009649 pregnancies were included in the analysis, of which 742 presented with RFM<\/jats:styled-content>, 1494 gave birth to an SGA<\/jats:styled-content> newborn and 53 were complicated by stillbirth after 36\u2009weeks' gestation. Logistic regression analysis showed a significant and independent association between UtA\u2010PI<\/jats:styled-content> and RFM<\/jats:styled-content> (odds ratio (OR<\/jats:styled-content>), 5.03 (95% CI<\/jats:styled-content>, 4.21\u20136.01); P<\/jats:italic>\u2009<\u20090.001), SGA<\/jats:styled-content> (OR<\/jats:styled-content> 2.41 (95% CI<\/jats:styled-content>, 2.09\u20132.79); P<\/jats:italic>\u2009<\u20090.001) and stillbirth (OR<\/jats:styled-content> 1.55 (95% CI<\/jats:styled-content>, 1.21\u20131.98); P<\/jats:italic><\u20090.001). The association between UtA\u2010PI<\/jats:styled-content> and SGA<\/jats:styled-content> was significantly stronger in women presenting with RFM<\/jats:styled-content> than in the rest of the cohort (P<\/jats:italic>\u2009<\u20090.001). Similarly the association between UtA\u2010PI<\/jats:styled-content> and RFM<\/jats:styled-content> was significantly stronger in those pregnancies complicated by stillbirth (P<\/jats:italic>\u2009<\u20090.001).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Compared with normal pregnancies, those complicated by RFM<\/jats:styled-content>, SGA<\/jats:styled-content> and stillbirth at term had higher UtA\u2010PI<\/jats:styled-content> at 19\u201323\u2009weeks' gestation. These findings support the assertion that RFM<\/jats:styled-content> at term is independently related to placental dysfunction and subsequent risk for SGA<\/jats:styled-content> and stillbirth. Copyright \u00a9 2013 ISUOG. Published by John Wiley & Sons Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.13220","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T02:26:08Z","timestamp":1381544768000},"page":"548-552","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Association between reduced fetal movements at term and abnormal uterine artery Doppler indices"],"prefix":"10.1002","volume":"43","author":[{"given":"G.","family":"Pagani","sequence":"first","affiliation":[{"name":"Fetal Medicine Unit, Division of Developmental Sciences St George's Medical School London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"D'Antonio","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Division of Developmental Sciences St George's Medical School London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Khalil","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Division of Developmental Sciences St George's Medical School London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Akolekar","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Division of Developmental Sciences St George's Medical School London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Papageorghiou","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Division of Developmental Sciences St George's Medical School London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Bhide","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Division of Developmental Sciences St George's Medical School London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Thilaganathan","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Division of Developmental Sciences St George's Medical School London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,15]]},"reference":[{"key":"e_1_2_5_2_1","volume-title":"Confidential Enquiry into Stillbirths and Deaths in Infancy. 3rd Annual Report","author":"Maternal and Child Health Research Consortium","year":"1995"},{"key":"e_1_2_5_3_1","volume-title":"Perinatal mortality","author":"Centre for Maternal and Child Enquiries (CMACE)","year":"2009"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-11-S3-S5"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6021.1305"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.110697"},{"key":"e_1_2_5_7_1","first-page":"53","article-title":"Case\u2013control study of factors associated with intrauterine deaths","volume":"6","author":"Efkarpidis S","year":"2004","journal-title":"MedGedMed"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/01443610801912618"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034851"},{"issue":"1","key":"e_1_2_5_10_1","first-page":"OP19.04","article-title":"Reduced fetal movements at term: association to first trimester uterine artery Doppler assessment","volume":"42","author":"Pagani G","year":"2013","journal-title":"Ultrasound Obstet Gynecol"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039784"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh037"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2007.070006"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.4057"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12371"},{"key":"e_1_2_5_16_1","unstructured":"National Collaborating Centre for Women's and Children's Health (UK).Antenatal care: Routine care for the healthy pregnant woman. 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