{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T13:14:28Z","timestamp":1772370868380,"version":"3.50.1"},"reference-count":8,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,3,3]],"date-time":"2014-03-03T00:00:00Z","timestamp":1393804800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Two cases of ultrasound diagnosis of Holt\u2013Oram syndrome are described. Both were characterized by significant right atrial enlargement that was not due to concurrent tricuspid regurgitation or other cardiac anomalies. In both cases the associated skeletal anomaly was subtle and barely visible using ultrasound. Interestingly, despite the fact that Holt\u2013Oram syndrome is also called atriodigital dysplasia, unexplained right atrial enlargement has not been described in this context in the fetus before. When such a finding is detected, we believe a thorough search for upper limb abnormalities should be carried out and genetic testing for Holt\u2013Oram syndrome should be discussed with the parents. Copyright \u00a9 2013 ISUOG. Published by John Wiley &amp; Sons Ltd<\/jats:italic>.<\/jats:p>","DOI":"10.1002\/uog.13238","type":"journal-article","created":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T22:07:20Z","timestamp":1383343640000},"page":"475-476","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Unexplained right atrial enlargement may be a sign of Holt\u2013Oram syndrome in the fetus"],"prefix":"10.1002","volume":"43","author":[{"given":"D.","family":"Paladini","sequence":"first","affiliation":[{"name":"Fetal Medicine and Surgery Unit - G.Gaslini Institute Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Tiesi","sequence":"additional","affiliation":[{"name":"Fetal Medicine and Surgery Unit - G.Gaslini Institute Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Buffi","sequence":"additional","affiliation":[{"name":"Fetal Medicine and Surgery Unit - G.Gaslini Institute Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Tuo","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology - G.Gaslini Institute Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Marasini","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology - G.Gaslini Institute Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,3]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.22.2.236"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0197-30"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19961016)65:2<128::AID-AJMG9>3.0.CO;2-O"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-34573"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-200212000-00008"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970080303"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2004.23.7.983"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-4520.2008.00211.x"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.13238","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.13238","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T04:03:22Z","timestamp":1696478602000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.13238"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,3]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1002\/uog.13238"],"URL":"https:\/\/doi.org\/10.1002\/uog.13238","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,3]]},"assertion":[{"value":"2013-08-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-03-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}