{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T21:23:30Z","timestamp":1770153810794,"version":"3.49.0"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,11,3]],"date-time":"2014-11-03T00:00:00Z","timestamp":1414972800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Fetal growth restriction is a strong risk factor for stillbirth. We compared the performance of three fetal growth curves\u00a0\u2013\u00a0customized, ultrasound (Hadlock) and population\u00a0\u2013\u00a0in identifying abnormally grown fetuses at risk of stillbirth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a case\u2013control study of singleton stillbirths (delivered between 2000 and 2010) at one center. Four liveborn controls were randomly identified for each stillbirth. Ultrasound\u2010estimated fetal weight within 1\u2009month prior to delivery was used to calculate growth percentiles for each fetus using three fetal growth norms. Sensitivities and odds ratios for stillbirth, as well as odds of abnormal growth according to formula, were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 49 stillbirths and 197 live births. Using the customized norms, growth of the fetuses destined to be stillborn was bimodal, with both more small\u2010for\u2010gestational\u2010age (<jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>; &lt;\u200910<jats:sup>th<\/jats:sup> percentile) and large\u2010for\u2010gestational\u2010age (<jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content>; \u2265\u200990<jats:sup>th<\/jats:sup> percentile) fetuses. Odds of being abnormally grown were significantly higher using ultrasound compared with population norms (<jats:italic>P<\/jats:italic>\u2009=\u20090.02) but were not statistically different using ultrasound and customized norms (<jats:italic>P<\/jats:italic>\u2009=\u20090.21). Sensitivity for identification of <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> on ultrasound as a predictor of stillbirth was higher using customized (39%; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 24\u201354%) or ultrasound (33%; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 19\u201347%), rather than population (14%; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 4\u201325%), norms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Among fetuses destined to be stillborn, customized and ultrasound norms identified a greater proportion of both <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content> estimated fetal weights. The customized norms performed best in identifying death among <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> fetuses. These results should be interpreted within the limitations of the study design. Copyright \u00a9 2014 ISUOG. Published by John Wiley &amp; Sons Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.13333","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T11:14:48Z","timestamp":1392635688000},"page":"595-599","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Identification of pathologically small fetuses using customized, ultrasound and population\u2010based growth norms"],"prefix":"10.1002","volume":"44","author":[{"given":"N. A.","family":"Smith","sequence":"first","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology Brigham and Women's Hospital  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Bukowski","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology University of Texas Medical Branch  Galveston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology Brigham and Women's Hospital  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Cantonwine","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology Brigham and Women's Hospital  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Zera","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology Brigham and Women's Hospital  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. N.","family":"Robinson","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology Brigham and Women's Hospital  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,11,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.08.055"},{"key":"e_1_2_5_3_1","volume-title":"The Investigation and Management of the Small for Gestational Age Fetus","author":"Royal College of Obstetricians and Gynaecologists Guideline Number 31","year":"2014"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.181.1.1887021"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2003.22.4.359"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.115865"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181704e48"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1997.16.4.241"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2006.108621"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2001.00205.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00656.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2010.506566"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01273.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31823dc56e"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq399"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1987.tb02336.x"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.13333","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.13333","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T04:30:20Z","timestamp":1696480220000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.13333"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1002\/uog.13333"],"URL":"https:\/\/doi.org\/10.1002\/uog.13333","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"2013-10-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-01-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-11-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}