{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:10:23Z","timestamp":1788869423426,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,8,25]],"date-time":"2014-08-25T00:00:00Z","timestamp":1408924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Twins and Multiple Births Association (Tamba)"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To generate reference charts for expected fetal growth in dichorionic diamniotic (\n                      <jats:styled-content style=\"fixed-case\">DCDA<\/jats:styled-content>\n                      ) and monochorionic diamniotic (\n                      <jats:styled-content style=\"fixed-case\">MCDA<\/jats:styled-content>\n                      ) twin pregnancies and to compare these with those from singleton pregnancies.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This was a retrospective study of biometric measurements from serial ultrasound examinations of twin pregnancies in the second and third trimesters, from 14 weeks' gestation to term, collected by nine hospitals over a 10\u2010year period. The measurements obtained in each fetus at each examination included head circumference (\n                      <jats:styled-content style=\"fixed-case\">HC<\/jats:styled-content>\n                      ), biparietal diameter (\n                      <jats:styled-content style=\"fixed-case\">BPD<\/jats:styled-content>\n                      ), abdominal circumference (\n                      <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>\n                      ) and femur length (\n                      <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content>\n                      ). Multilevel mixed effects statistical models were used to evaluate growth in each biometric variable in relation to gestational age, taking account of the serial examinations and the association between the two fetuses in each pregnancy, with separate models constructed for\n                      <jats:styled-content style=\"fixed-case\">DCDA<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">MCDA<\/jats:styled-content>\n                      pregnancies.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The final dataset for analysis included a total of 9866 second\u2010 and third\u2010trimester ultrasound examinations in 1802\n                      <jats:styled-content style=\"fixed-case\">DCDA<\/jats:styled-content>\n                      and 323\n                      <jats:styled-content style=\"fixed-case\">MCDA<\/jats:styled-content>\n                      twin pregnancies, with a median of five (range, 1\u201314) scans per pregnancy. For each variable, the mean value for\n                      <jats:styled-content style=\"fixed-case\">DCDA<\/jats:styled-content>\n                      twins was close to the reported value in singletons at 20\u201330 weeks and showed a decrease relative to singletons beyond 30 weeks. The differences were greater for\n                      <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">HC<\/jats:styled-content>\n                      , for which the mean in twins was approximately equivalent to the 30\n                      <jats:sup>th<\/jats:sup>\n                      percentile in singletons at 18 weeks, the 35\n                      <jats:sup>th<\/jats:sup>\n                      percentile at 25 weeks and the 30\n                      <jats:sup>th<\/jats:sup>\n                      percentile at 35 weeks. Fetuses in\n                      <jats:styled-content style=\"fixed-case\">MCDA<\/jats:styled-content>\n                      twin pregnancies displayed lower mean measurements than did those in\n                      <jats:styled-content style=\"fixed-case\">DCDA<\/jats:styled-content>\n                      pregnancies throughout the gestational age range considered.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Ultrasound biometry shows a small but statistically significant reduction in fetal growth in twin pregnancies relative to that in singletons, particularly in the third trimester, with a more marked difference for\n                      <jats:styled-content style=\"fixed-case\">MCDA<\/jats:styled-content>\n                      than for DCDA pregnancies. Copyright \u00a9 2014 ISUOG. Published by John Wiley &amp; Sons Ltd.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/uog.14640","type":"journal-article","created":{"date-parts":[[2014,7,23]],"date-time":"2014-07-23T06:11:10Z","timestamp":1406095870000},"page":"301-307","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":106,"title":["Fetal growth reference ranges in twin pregnancy: analysis of the Southwest Thames Obstetric Research Collaborative (\n                    <scp>STORK<\/scp>\n                    ) multiple pregnancy cohort"],"prefix":"10.1002","volume":"45","author":[{"given":"O. T.","family":"Stirrup","sequence":"first","affiliation":[{"name":"MRC Clinical Trials Unit at UCL University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Khalil","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Division of Developmental Sciences St George's University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"D'Antonio","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Division of Developmental Sciences St George's University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Thilaganathan","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Division of Developmental Sciences St George's University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Southwest Thames Obstetric Research Collaborative (STORK)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,8,25]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Multiple pregnancy: the management of twin and triplet pregnancies in the antenatal period. 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