{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T08:53:50Z","timestamp":1784364830158,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,3,4]],"date-time":"2016-03-04T00:00:00Z","timestamp":1457049600000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet & Gyne"],"published-print":{"date-parts":[[2016,3]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>Twin anemia\u2013polycythemia sequence (TAPS<\/jats:styled-content>) can occur as a unique disease or as a complication of twin\u2013twin transfusion syndrome (TTTS<\/jats:styled-content>). Middle cerebral artery (MCA<\/jats:styled-content>) Doppler studies are not currently part of the routine evaluation of monochorionic twins since they are not used in the Quintero staging system. As such, the true incidence of TAPS<\/jats:styled-content> is unknown. We aimed to compare the characteristics and outcomes of twin pregnancies with TTTS<\/jats:styled-content> complicated by spontaneous anemia\u2013polycythemia vs<\/jats:italic> those with TTTS<\/jats:styled-content> alone.<\/jats:p><\/jats:sec>Methods<\/jats:title>This was a secondary analysis of data collected prospectively from a cohort of 156 consecutive patients undergoing fetoscopic laser surgery for TTTS<\/jats:styled-content>, between October 2011 and August 2014. TAPS<\/jats:styled-content> was defined as discordance in the preoperative MCA<\/jats:styled-content> peak systolic velocity (PSV<\/jats:styled-content>), with one twin fetus having MCA\u2010PSV<\/jats:styled-content> \u2264\u20091.0 multiples of the median (MoM<\/jats:styled-content>) and the other having MCA\u2010PSV<\/jats:styled-content> \u2265 1.5 MoM<\/jats:styled-content>. Maternal demographics as well as preoperative, operative and postoperative variables were analyzed.<\/jats:p><\/jats:sec>Results<\/jats:title>Included in the final analysis were 133 patients with complete records: 11 cases with TTTS<\/jats:styled-content> with anemia\u2013polycythemia and 122 cases with TTTS<\/jats:styled-content> alone. There was no difference in maternal body mass index, gestational age (GA<\/jats:styled-content>) at procedure, rate of preterm prelabor rupture of membranes or GA<\/jats:styled-content> at delivery between the two groups. Patients with TTTS<\/jats:styled-content> and anemia\u2013polycythemia were more likely to be older (P<\/jats:italic>\u2009=\u20090.03) and parous (P<\/jats:italic>\u2009=\u20090.04) and had a significantly lower number of placental anastomoses (P<\/jats:italic>\u2009=\u20090.01). The dual live\u2010birth rate was similar for both groups (P<\/jats:italic>\u2009=\u20090.76).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Cases of TTTS<\/jats:styled-content> with anemia\u2013polycythemia were more likely to be found in parous and older women and were characterized by fewer vascular anastomoses. TTTS<\/jats:styled-content> with anemia\u2013polycythemia was not associated with worse perinatal outcome after laser therapy. Copyright \u00a9 2015 ISUOG. Published by John Wiley & Sons Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.14913","type":"journal-article","created":{"date-parts":[[2015,5,29]],"date-time":"2015-05-29T17:31:52Z","timestamp":1432920712000},"page":"340-344","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Does anemia\u2013polycythemia complicating twin\u2013twin transfusion syndrome affect outcome after fetoscopic laser surgery?"],"prefix":"10.1002","volume":"47","author":[{"given":"R.","family":"Donepudi","sequence":"first","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences UT Health School of Medicine Houston TX USA"},{"name":"The Fetal Center at Children's Memorial Hermann Hospital Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Papanna","sequence":"additional","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences UT Health School of Medicine Houston TX USA"},{"name":"The Fetal Center at Children's Memorial Hermann Hospital Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Snowise","sequence":"additional","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences UT Health School of Medicine Houston TX USA"},{"name":"The Fetal Center at Children's Memorial Hermann Hospital Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences UT Health School of Medicine Houston TX USA"},{"name":"The Fetal Center at Children's Memorial Hermann Hospital Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bebbington","sequence":"additional","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences UT Health School of Medicine Houston TX USA"},{"name":"The Fetal Center at Children's Memorial Hermann Hospital Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"K. J.","family":"Moise","sequence":"additional","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences UT Health School of Medicine Houston TX USA"},{"name":"The Fetal Center at Children's Memorial Hermann Hospital Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,3,4]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032597"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2006.01.010"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2491"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.05.009"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.03.050"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.08.062"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.08.069"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7200292"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.13382"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000304512"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(199809)18:9<941::AID-PD427>3.0.CO;2-G"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000365919"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2012.01.009"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2013.02.005"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4177"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2012.09.025"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318187e1ff"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2013.04.005"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1159\/000319803"}],"container-title":["Ultrasound in Obstetrics & Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.14913","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.14913","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.14913","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T19:21:52Z","timestamp":1696360912000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.14913"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1002\/uog.14913"],"URL":"https:\/\/doi.org\/10.1002\/uog.14913","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"2015-02-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-05-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-03-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}