{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T20:08:24Z","timestamp":1770235704502,"version":"3.49.0"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,2,2]],"date-time":"2016-02-02T00:00:00Z","timestamp":1454371200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the need for postnatal neurosurgical intervention after fetoscopic patch coverage of spina bifida aperta (<jats:styled-content style=\"fixed-case\">SBA<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective analysis of a cohort of 71 fetuses which underwent minimally invasive fetoscopic patch coverage of <jats:styled-content style=\"fixed-case\">SBA<\/jats:styled-content> between 21 + 0 and 29 + 1 weeks of gestation. Postnatal neurosurgical procedures were classified into two types: re\u2010coverage of the <jats:styled-content style=\"fixed-case\">SBA<\/jats:styled-content> within the first 3 months following birth, and shunt placement as treatment of associated hydrocephalus within the first year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Location of the <jats:styled-content style=\"fixed-case\">SBA<\/jats:styled-content> was lumbosacral in 59 cases, lumbar in seven, thoracic in three and sacral in two. In total, 20\/71 (28%) patients underwent early postnatal neurosurgical intervention by means of re\u2010coverage of the <jats:styled-content style=\"fixed-case\">SBA<\/jats:styled-content>. This was performed because of cerebrospinal fluid leakage in seven (35%), adhesions with functional deterioration in three (15%), incomplete coverage in five (25%) and skin defect in five (25%) cases. Ventriculoperitoneal shunt placement within 1 year was required in 32 (45%) cases and was preceded by ventriculostomy in two. Three (4%) infants needed Chiari decompression surgery in the first 12 months following birth, because of syringomyelia or gait disturbance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Fetoscopic patch coverage of <jats:styled-content style=\"fixed-case\">SBA<\/jats:styled-content> may require postnatal re\u2010coverage in some cases. In most cases, conservative wound treatment shows good results, without requiring neurosurgical intervention. The low 1\u2010year\u2010shunt rate is comparable to data of the Management of Myelomeningocele Study and lower compared with published data of patients with postnatal only coverage of <jats:styled-content style=\"fixed-case\">SBA<\/jats:styled-content>. Copyright \u00a9 2015 ISUOG. Published by John Wiley &amp; Sons Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.14937","type":"journal-article","created":{"date-parts":[[2015,7,3]],"date-time":"2015-07-03T16:02:49Z","timestamp":1435939369000},"page":"158-161","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":66,"title":["Percutaneous minimally invasive fetoscopic surgery for spina bifida aperta. Part III: neurosurgical intervention in the first postnatal year"],"prefix":"10.1002","volume":"47","author":[{"given":"K.","family":"Graf","sequence":"first","affiliation":[{"name":"Department of Neurosurgery Justus\u2010Liebig\u2010University  Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Kohl","sequence":"additional","affiliation":[{"name":"German Center for Fetal Surgery &amp; Minimally Invasive Therapy (DZFT) Justus\u2010Liebig\u2010University  Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. A.","family":"Neubauer","sequence":"additional","affiliation":[{"name":"Department of Neuropediatrics Justus\u2010Liebig\u2010University  Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Dey","sequence":"additional","affiliation":[{"name":"Department of Neuropediatrics Justus\u2010Liebig\u2010University  Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Faas","sequence":"additional","affiliation":[{"name":"Department of General Pediatrics and Neonatology Justus\u2010Liebig\u2010University  Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. A.","family":"Wanis","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Justus\u2010Liebig\u2010University  Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. H. T.","family":"Reinges","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Justus\u2010Liebig\u2010University  Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Uhl","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Justus\u2010Liebig\u2010University  Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. A.","family":"Kolodziej","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Justus\u2010Liebig\u2010University  Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,2]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199911113412006"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)91022-6"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)17445-X"},{"key":"e_1_2_5_5_1","first-page":"65","article-title":"Technique for closure of myelomeningocele","volume":"6","author":"McLone DG","year":"1980","journal-title":"Childs Brain"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1014379"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2012.10.003"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2011.04049.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.19.1826"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000028859"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.3171\/2011.12.PEDS11403"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.13430"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.13389"},{"key":"e_1_2_5_14_1","first-page":"632","article-title":"Long\u2010term outcome in open spina bifida","volume":"54","author":"Oakeshott P","year":"2003","journal-title":"Br J Gen Pract"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.3171\/2013.4.PEDS12616"},{"key":"e_1_2_5_16_1","first-page":"397","article-title":"Comparison of simultaneous shunting to delayed shunting in infants with myelomeningocele in terms of shunt infection rate","volume":"21","author":"Arslan M","year":"2011","journal-title":"Turk Neurosurg"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1071027"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2013.858689"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.14937","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.14937","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T17:42:23Z","timestamp":1738345343000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.14937"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1002\/uog.14937"],"URL":"https:\/\/doi.org\/10.1002\/uog.14937","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2]]},"assertion":[{"value":"2015-01-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-06-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-02-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}