{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T18:53:27Z","timestamp":1791140007481,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,4,6]],"date-time":"2016-04-06T00:00:00Z","timestamp":1459900800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate short\u2010 and long\u2010term effects on residual myometrial thickness (<jats:styled-content style=\"fixed-case\">RMT<\/jats:styled-content>) of adding a second layer to a single unlocked closure of a Cesarean uterine incision.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a randomized double\u2010blind controlled trial. Healthy nulliparous women scheduled for first\u2010time elective Cesarean delivery were operated on using a modified version of the Misgav Ladach surgical technique. The women were examined by transabdominal ultrasound before discharge from the maternity ward and by transvaginal saline contrast sonohysterography at a minimum of 5 months postpartum.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010six nulliparae met the criteria and agreed to participate in the study. Thirty\u2010five women were assigned to the single\u2010layer technique and 38 to the double\u2010layer unlocked closure technique. Groups were comparable regarding gestational age at delivery, duration of surgery and perioperative blood loss. There was no difference in <jats:styled-content style=\"fixed-case\">RMT<\/jats:styled-content> between the two groups, both at time of discharge (mean \u00b1 <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>, 20.2 \u00b1 8.0 mm <jats:italic>vs<\/jats:italic> 21.0 \u00b1 9.7 mm) and after 5 months postpartum (mean, 5.7 \u00b1 2.9 mm <jats:italic>vs<\/jats:italic> 5.7 \u00b1 2.2 mm). <jats:styled-content style=\"fixed-case\">RMT<\/jats:styled-content> was approximately half that of the normal myometrium at both examinations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results of this study  suggest that double\u2010layer closure of a Cesarean uterine incision does not increase <jats:styled-content style=\"fixed-case\">RMT<\/jats:styled-content> compared with single\u2010layer closure when an unlocked technique is used. Copyright \u00a9 2015 ISUOG. Published by John Wiley &amp; Sons Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.15792","type":"journal-article","created":{"date-parts":[[2015,10,22]],"date-time":"2015-10-22T08:30:15Z","timestamp":1445502615000},"page":"417-422","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Impact of adding a second layer to a single unlocked closure of a Cesarean uterine incision: randomized controlled trial"],"prefix":"10.1002","volume":"47","author":[{"given":"G.","family":"Bennich","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Roskilde University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Rudnicki","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Odense University Hospital  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Wilken\u2010Jensen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Hvidovre University Hospital  Hvidovre Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Lousen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Roskilde University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. D.","family":"Lassen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Roskilde University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"W\u00f8jdemann","sequence":"additional","affiliation":[{"name":"Department of Surgery Bornholms Hospital  Roenne Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,4,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.03.063"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181e41be3"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.329.7456.19"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2011.04.013"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)90464-X"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7496"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000284628.29796.80"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2013.11.013"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/2278-960X.112591"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.1999.780709.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318209abf0"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/2229-3485.83221"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.13199"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12376"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2012.01872.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003300050103"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13015"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13095"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.15792","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.15792","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T07:16:19Z","timestamp":1696490179000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.15792"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["10.1002\/uog.15792"],"URL":"https:\/\/doi.org\/10.1002\/uog.15792","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4]]},"assertion":[{"value":"2015-03-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-10-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-04-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}