{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T06:58:09Z","timestamp":1780383489340,"version":"3.54.1"},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,4,3]],"date-time":"2017-04-03T00:00:00Z","timestamp":1491177600000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the accuracy of magnetic resonance enema (<jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\u2010e) and rectal water\u2010contrast transvaginal sonography (<jats:styled-content style=\"fixed-case\">RWC\u2010TVS<\/jats:styled-content>) in the diagnosis of rectosigmoid endometriosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective study included 286 patients of reproductive age with clinical suspicion of rectosigmoid endometriosis. Patients underwent <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\u2010e and <jats:styled-content style=\"fixed-case\">RWC\u2010TVS<\/jats:styled-content> before laparoscopic excision of endometriotic lesions. The findings of <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\u2010e and <jats:styled-content style=\"fixed-case\">RWC\u2010TVS<\/jats:styled-content> were compared with surgical and histological results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 286 patients included in the study, 151 (52.8%) had rectosigmoid endometriosis. <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\u2010e and <jats:styled-content style=\"fixed-case\">RWC\u2010TVS<\/jats:styled-content> had similar accuracy in the diagnosis of rectosigmoid endometriosis (<jats:italic>P<\/jats:italic>\u2009=\u20090.063). In the diagnosis of rectosigmoid endometriosis with <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\u2010e, the sensitivity was 95.4% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 90.7\u201399.1%),  specificity was 97.8% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 93.6\u201399.5%), positive predictive value (PPV) was 98.0% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 94.1\u201399.6%), negative predictive value (NPV) was 95.0% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 89.9\u201397.9%),  positive likelihood ratio (LR+) was 42.91 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 14.01\u2013131.46) and negative likelihood ratio  (LR\u2212) was 0.05 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 0.02\u20130.10). For diagnosis with <jats:styled-content style=\"fixed-case\">RWC\u2010TVS<\/jats:styled-content>, sensitivity was 92.7% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 87.3\u201396.3%), specificity was 97.0% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 92.6\u201399.2%), PPV was 97.2% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 93.0\u201399.2%), NPV was 92.3% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 86.6\u201396.1%), LR+ was 31.29 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 11.90\u201382.25) and LR\u2212 was 0.08 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 0.04\u20130.13). <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\u2010e and <jats:styled-content style=\"fixed-case\">RWC\u2010TVS<\/jats:styled-content> underestimated the size of the endometriotic nodules; for both imaging techniques the underestimation was greater for nodules with a diameter\u2009\u2265\u200930\u2009mm. There was no significant difference in the mean intensity of pain experienced by the patients during the two examinations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">RWC\u2010TVS<\/jats:styled-content> should be the first\u2010line investigation in patients with clinical suspicion of rectosigmoid endometriosis and physicians should be trained in performing this examination. Considering that <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\u2010e is more expensive than <jats:styled-content style=\"fixed-case\">RWC\u2010TVS<\/jats:styled-content>, it should be used only when the findings of <jats:styled-content style=\"fixed-case\">RWC\u2010TVS<\/jats:styled-content> are unclear. Copyright \u00a9 2016 ISUOG. Published by John Wiley &amp; Sons Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.15934","type":"journal-article","created":{"date-parts":[[2016,4,10]],"date-time":"2016-04-10T18:28:53Z","timestamp":1460312933000},"page":"524-532","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Magnetic resonance enema <i>vs<\/i> rectal water\u2010contrast transvaginal sonography in diagnosis of rectosigmoid endometriosis"],"prefix":"10.1002","volume":"49","author":[{"given":"U.","family":"Leone Roberti Maggiore","sequence":"first","affiliation":[{"name":"Academic Unit of Obstetrics and Gynaecology IRCCS AOU San Martino\u00a0\u2013\u00a0IST  Genoa Italy"},{"name":"Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI) University of Genoa  Genoa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Biscaldi","sequence":"additional","affiliation":[{"name":"Department of Radiology Galliera Hospital  Genoa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. 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