{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T03:11:08Z","timestamp":1767237068231},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,2,17]],"date-time":"2005-02-17T00:00:00Z","timestamp":1108598400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2005,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To explore the relationship between cerebroplacental Doppler impedance index and birth weight in postdates pregnancies, and to evaluate the use of a combination of Doppler parameters and ultrasound biometry in the prediction of large\u2010for\u2010gestational age (LGA) fetuses at 41 weeks of gestation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The pulsatility indices of the umbilical (UA\u2010PI) and middle cerebral (MCA\u2010PI) arteries, the cerebroplacental pulsatility index ratio (CPR) and the estimated fetal weight (EFW) were obtained in a cohort of 181 ultrasound\u2010dated pregnancies at 41 weeks' gestation, 2 days before induction of delivery. A regression equation was established and the correlation between umbilical artery impedance and different birth\u2010weight centile groups was determined. A receiver\u2013operating characteristics (ROC) curve was used to compare prediction of LGA fetuses using biometry alone with that using biometry and UA\u2010PI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>UA\u2010PI was inversely related to EFW (Spearson's correlation coefficient rho = \u22120.28, <jats:italic>P<\/jats:italic> &lt; 0.001). Logistic regression showed an independent contribution of UA\u2010PI to the birth\u2010weight estimation (birth <jats:italic>weight<\/jats:italic> = 1356.8 \u2212 232.0 \u00d7 <jats:italic>UA<\/jats:italic>\u2010<jats:italic>PI<\/jats:italic> + 0.65 \u00d7 <jats:italic>EFW<\/jats:italic>). On ROC curve analysis, the prediction of LGA with the regression equation was comparable to that using ultrasound biometry alone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>UA\u2010PI was inversely correlated to EFW, but the combination of ultrasound biometry and UA\u2010PI compared with biometry alone showed similar prediction of LGA fetuses in postdates pregnancies. Further prospective trials on larger populations or groups with a higher prevalence of LGA fetuses would be needed to validate the use of the new formula. Copyright \u00a9 2005 ISUOG. 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