{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T04:28:48Z","timestamp":1770352128774,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T00:00:00Z","timestamp":1533254400000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Perelman Family Foundation"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Fetuses with growth restriction have been reported to have an abnormal sphericity index (SI), which is indicative of the shape of the ventricular chambers of the heart. Our aim was to evaluate the SI for 24 transverse segments distributed from base to apex of the right (RV) and left (LV) ventricles to determine whether, in small\u2010for\u2010gestational\u2010age (SGA) fetuses, the SI is abnormal at locations other than the basal segment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We evaluated 30 SGA fetuses between 25 and 37\u2009weeks of gestation. SI was computed for both ventricles by dividing the end\u2010diastolic mid\u2010basal\u2013apical length by each of 24 end\u2010diastolic transverse segmental widths, from base (Segment 1) to apex (Segment 24). For each ventricle, the <jats:italic>Z<\/jats:italic>\u2010score and centile for the SI from each of the 24 segments were computed using the mean and SD from published equations. The 24\u2010segment method, defining abnormal SI as values &lt;\u200910<jats:sup>th<\/jats:sup> centile or &gt;\u200990<jats:sup>th<\/jats:sup> centile, was compared with that of using only the basal segment by chi\u2010square analysis to determine the number of fetuses identified with an abnormal SI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 23 of the 30 (77%) SGA fetuses, at least one of the 24 transverse segments in one or both ventricles had an abnormal SI; in 17% of cases, both ventricles were affected, in 23% of cases only the RV was involved and in 37% of cases only the LV was involved. Compared with the 24\u2010segment model, significantly fewer fetuses with an abnormal SI were identified using only basal Segment 1, from the RV base (58%, 7\/12; <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.01) or only Segment 12, in the mid portion of the RV (50%, 6\/12; <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.005). Combining measurements of Segment 1 and Segment 12 from the RV identified 83% of fetuses with at least one abnormal SI and was not significantly different from using the 24\u2010segment model. Similarly, significantly fewer fetuses with an abnormal SI were identified using only LV basal Segment 1 (63%, 10\/16; <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.006) or only Segment 12, in the mid portion of the LV (75%, 12\/16; <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.03), when compared with the 24\u2010segment model. Combining measurements of both LV Segment 1 and Segment 12 identified 81% (13\/16) of fetuses with an abnormal SI and was not significantly different from using the 24\u2010segment model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The 24\u2010segment SI of RV and LV provides a comprehensive method with which to examine the shape of the ventricular chambers and identifies more SGA fetuses with an abnormal SI than are identified using only the basal segment SI. Copyright \u00a9 2017 ISUOG. Published by John Wiley &amp; Sons Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.18820","type":"journal-article","created":{"date-parts":[[2017,7,26]],"date-time":"2017-07-26T11:16:42Z","timestamp":1501067802000},"page":"243-249","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Right and left ventricular 24\u2010segment sphericity index is abnormal in small\u2010for\u2010gestational\u2010age fetuses"],"prefix":"10.1002","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8814-572X","authenticated-orcid":false,"given":"G. R.","family":"DeVore","sequence":"first","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine, Department of Obstetrics and Gynecology David Geffen School of Medicine at UCLA  Los Angeles CA USA"},{"name":"Fetal Diagnostic Centers, Pasadena Tarzana and Lancaster  CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Zaretsky","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Colorado School of Medicine  Denver CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. L.","family":"Gumina","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Colorado School of Medicine  Denver CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. C.","family":"Hobbins","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Colorado School of Medicine  Denver CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,8,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jep114"},{"key":"e_1_2_6_3_1","volume-title":"Pathologic Basis Of Disease","author":"Schoen FJ","year":"1999"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/14.suppl_C.24"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-121-5-199409010-00009"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2005.04051.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000099057"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.20131"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.10.027"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2010.01.029"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.111.970012"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2013.05.007"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2014.11.008"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.256"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.002428"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5273(93)90207-W"},{"key":"e_1_2_6_17_1","first-page":"107","article-title":"Left ventricular function and geometry in juvenile mitral stenosis","volume":"46","author":"Mohan JC","year":"1994","journal-title":"Indian Heart J"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(96)90166-0"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00059-4"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14688"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15767"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.17365"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14930"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.12.031"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.17505"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.7863\/ultra.15.08060"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.152.2.6739822"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(85)90298-4"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.05.024"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.4960241106"},{"key":"e_1_2_6_31_1","first-page":"114","volume-title":"Fundamental and Advanced Fetal Imaging \u2010 Ultrasound and MRI","author":"Devore GR","year":"2015"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.18820","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.18820","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T19:41:37Z","timestamp":1694893297000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.18820"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["10.1002\/uog.18820"],"URL":"https:\/\/doi.org\/10.1002\/uog.18820","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"2017-04-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}