{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:04:26Z","timestamp":1790791466687,"version":"4.1.0"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,10,4]],"date-time":"2018-10-04T00:00:00Z","timestamp":1538611200000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate whether abdominal circumference growth velocity (ACGV) improves the prediction of perinatal outcome in small\u2010for\u2010gestational\u2010age (SGA) fetuses beyond that afforded by estimated fetal weight (EFW) and cerebroplacental ratio (CPR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cohort of 235 singleton SGA fetuses at 36\u201338\u2009weeks' gestation was examined. ACGV, EFW and CPR centiles were calculated. ACGV centile was determined using data from a large database of 19\u201321\u2010 and 36\u201338\u2010week scans in an unselected population. Binary variables of ACGV &lt;\u200910<jats:sup>th<\/jats:sup>, EFW &lt;\u20093<jats:sup>rd<\/jats:sup> and CPR\u2009&lt;\u20095<jats:sup>th<\/jats:sup> centiles were defined as abnormal. Two composite adverse outcomes (CAO) were explored: CAO\u20101 defined as at least one of umbilical artery pH\u2009&lt;\u20097.10, 5\u2010min Apgar score\u2009&lt;\u20097 or neonatal unit admission, and CAO\u20102 that included in addition hypoglycemia, intrapartum fetal distress and perinatal death. Univariate and multivariate logistic regression analyses were performed to analyze the relationship between the three risk factors and their predictive value for CAO. The change in screening performance afforded by adding ACGV to EFW and CPR was assessed and receiver\u2013operating characteristics (ROC) curves were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>ACGV &lt;\u200910<jats:sup>th<\/jats:sup> centile was an independent risk factor for CAO. The sensitivity, specificity, positive and negative likelihood ratios of a predictive model based on EFW\u2009&lt;\u20093<jats:sup>rd<\/jats:sup> centile and CPR\u2009&lt;\u20095<jats:sup>th<\/jats:sup> centile were, respectively, 51%, 70%, 1.71 and 0.69 for CAO\u20101 and 41%, 70%, 1.39 and 0.83 for CAO\u20102. After addition of ACGV &lt;\u200910<jats:sup>th<\/jats:sup> centile to the model, the respective values were 82%, 46%, 1.54 and 0.38 for CAO\u20101 and 71%, 47%, 1.34 and 0.62 for CAO\u20102. Using continuous variables, the areas under the ROC curves improved marginally from 0.669 (95% CI, 0.604\u20130.729) to 0.741 (95% CI, 0.677\u20130.798) for CAO\u20101 and from 0.646 (95% CI, 0.580\u20130.707) to 0.700 (95% CI, 0.633\u20130.759) for CAO\u20102 after addition of ACGV to the model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>ACGV is a risk factor for adverse neonatal outcome that is independent of EFW and of CPR, although any improvement in the prediction of adverse outcome is not statistically significant. Copyright \u00a9 2017 ISUOG. Published by John Wiley &amp; Sons Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.18988","type":"journal-article","created":{"date-parts":[[2017,12,20]],"date-time":"2017-12-20T10:00:26Z","timestamp":1513764026000},"page":"494-500","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Using fetal abdominal circumference growth velocity in the prediction of adverse outcome in near\u2010term small\u2010for\u2010gestational\u2010age fetuses"],"prefix":"10.1002","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2539-2648","authenticated-orcid":false,"given":"A.","family":"Cavallaro","sequence":"first","affiliation":[{"name":"Fetal Medicine Unit, Department of Maternal and Fetal Medicine, Women's Centre, John Radcliffe Hospital Oxford University Hospitals NHS Foundation Trust  Oxford UK"},{"name":"Nuffield Department of Obstetrics and Gynaecology University of Oxford, John Radcliffe Hospital  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5140-5601","authenticated-orcid":false,"given":"M.","family":"Veglia","sequence":"additional","affiliation":[{"name":"Nuffield Department of Obstetrics and Gynaecology University of Oxford, John Radcliffe Hospital  Oxford UK"},{"name":"Department of Obstetrics and Gynaecology, Ospedale Cristo Re  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Svirko","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Department of Maternal and Fetal Medicine, Women's Centre, John Radcliffe Hospital Oxford University Hospitals NHS Foundation Trust  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Vannuccini","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Department of Maternal and Fetal Medicine, Women's Centre, John Radcliffe Hospital Oxford University Hospitals NHS Foundation Trust  Oxford UK"},{"name":"Nuffield Department of Obstetrics and Gynaecology University of Oxford, John Radcliffe Hospital  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6307-1912","authenticated-orcid":false,"given":"G.","family":"Volpe","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Department of Maternal and Fetal Medicine, Women's Centre, John Radcliffe Hospital Oxford University Hospitals NHS Foundation Trust  Oxford UK"},{"name":"Nuffield Department of Obstetrics and Gynaecology University of Oxford, John Radcliffe Hospital  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4462-112X","authenticated-orcid":false,"given":"L.","family":"Impey","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit, Department of Maternal and Fetal Medicine, Women's Centre, John Radcliffe Hospital Oxford University Hospitals NHS Foundation Trust  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,4]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2006.10.010"},{"key":"e_1_2_6_3_1","first-page":"453","article-title":"Intrauterine growth restriction: identification and management","volume":"58","author":"Peleg D","year":"1998","journal-title":"Am Fam Physician"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.01.036"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2012.06.039"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1111"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2004.tb00236.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15664"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000429658.85846.f9"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.13319"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15663"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14714"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00131-2"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.02.005"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.17471"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2008.02532.x"},{"key":"e_1_2_6_17_1","unstructured":"National Institute for Health and Care Excellence (NICE). 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