{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T06:10:04Z","timestamp":1760249404255,"version":"3.40.5"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,2,6]],"date-time":"2019-02-06T00:00:00Z","timestamp":1549411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Redistribution of cardiac output (CO) is responsible for the brain\u2010sparing effect seen during periods of fetal stress. Our aim was to investigate prospectively the correlation between fetoplacental Doppler indices and measurements of cardiac function in uncomplicated term singleton pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a prospective observational study of normotensive women with appropriately grown, non\u2010anomalous singleton pregnancy. Participants underwent fortnightly ultrasound examinations from 36\u2009weeks' gestation until delivery, and intrapartum and neonatal outcomes were recorded. The correlation between fetoplacental Doppler indices and various measurements of cardiac function was evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study cohort comprised 273 singleton pregnancies. The cerebroplacental ratio (CPR) was correlated positively with left ventricular CO (LVCO) (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001, rho\u2009=\u20090.29), left\u2010to\u2010right ventricular CO ratio (LVCO\/RVCO; <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001, rho\u00a0=\u20090.41), global left ventricular strain (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.01, rho\u2009=\u20090.17) and global right ventricular strain (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001, rho\u2009=\u20090.22). The CPR was correlated inversely with the left ventricular myocardial performance index (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.01, rho\u2009=\u2009\u20130.18) and the RVCO (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001, rho\u2009=\u2009\u20130.28). The LVCO and global left ventricular strain were correlated positively with umbilical venous flow (<jats:italic>P<\/jats:italic>\u00a0=\u20090.04, rho\u2009=\u20090.18 and <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001, rho\u2009=\u20090.25, respectively). There was minimal or no correlation between either the mean uterine artery pulsatility index (PI) or umbilical artery PI with any cardiac indices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The fetal CPR, middle cerebral artery PI and umbilical venous flow are correlated positively with LVCO, LVCO\/RVCO and global left ventricular strain in low\u2010risk term pregnancies. Copyright \u00a9 2018 ISUOG. Published by John Wiley &amp; Sons Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.19056","type":"journal-article","created":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T00:06:27Z","timestamp":1521936387000},"page":"358-366","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Correlation between fetoplacental Doppler indices and measurements of cardiac function in term fetuses"],"prefix":"10.1002","volume":"53","author":[{"given":"A. A.","family":"Alsolai","sequence":"first","affiliation":[{"name":"College of Applied Medical Science King Saud University  Riyadh Kingdom of Saudi Arabia"},{"name":"Faculty of Medicine The University of Queensland  Herston Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. 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