{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T17:58:49Z","timestamp":1788544729759,"version":"build-2803163510"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T00:00:00Z","timestamp":1554163200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the association between physical exercise during pregnancy and maternal gestational weight gain and fetal cardiac function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a randomized controlled trial of women with a singleton pregnancy managed from the first trimester at the Hospital de Torrej\u00f3n, Madrid, between November 2014 and June 2015. Women were randomized to either follow a supervised physical conditioning program, consisting of a 60\u2010min session 3\u2009days per week for the duration of pregnancy, or not attend any exercise program (controls). The primary outcome was maternal weight gain during pregnancy. Secondary outcomes included fetal cardiac function parameters evaluated at 20, 28 and 36\u2009weeks' gestation, Cesarean section, preterm delivery, induction of labor and birth weight. A sample size of 45 in each group was planned to detect differences in maternal weight gain of at least 1\u2009kg, with a power of &gt;\u200980% and \u03b1 of 0.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the study period, 120 women were randomized into the exercise (<jats:italic>n<\/jats:italic>\u00a0=\u200975) and control (<jats:italic>n<\/jats:italic>\u00a0=\u200945) groups. Following exclusions, the final cohort consisted of 42 women in the exercise group and 43 in the control group. Baseline characteristics (maternal age, prepregnancy body mass index, parity, conception by <jats:italic>in\u2010vitro<\/jats:italic> fertilization, Caucasian ethnicity, physical exercise prior to pregnancy and smoker) were similar between the two groups. No differences were found between the groups in maternal weight at 20, 28, 36 and 38\u2009weeks' gestation or in weight gain at 38\u2009weeks. However, the proportion of women with weight loss \u2265\u20099\u2009kg at 6\u2009weeks postpartum was higher in the exercise compared with the control group (68.2% <jats:italic>vs<\/jats:italic> 42.8%; relative risk 1.593; <jats:italic>P<\/jats:italic>\u00a0=\u20090.02). The ductus arteriosus pulsatility index (DA\u2010PI) at 20\u2009weeks (2.43\u2009\u00b1\u20090.40 <jats:italic>vs<\/jats:italic> 2.26\u2009\u00b1\u20090.33, <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.05) and the ejection fraction (EF) at 36\u2009weeks (0.85\u2009\u00b1\u20090.13 <jats:italic>vs<\/jats:italic> 0.81\u2009\u00b1\u20090.11, <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.05) were higher in the exercise compared with the control group. All other evaluated fetal cardiac function parameters were similar between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Performing exercise during pregnancy is not associated with a reduction in maternal weight gain but increases weight loss at 6\u2009weeks postpartum. Physical exercise during pregnancy is associated with increased fetal DA\u2010PI at 20\u2009weeks and EF at 36\u2009weeks, which could reflect adaptive mechanisms. Copyright \u00a9 2018 ISUOG. Published by John Wiley &amp; Sons Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.20147","type":"journal-article","created":{"date-parts":[[2018,10,17]],"date-time":"2018-10-17T09:08:06Z","timestamp":1539767286000},"page":"583-589","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Does exercise during pregnancy impact on maternal weight gain and fetal cardiac function? A randomized controlled trial"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1840-5087","authenticated-orcid":false,"given":"M.","family":"Brik","sequence":"first","affiliation":[{"name":"Fetal Medicine Department Hospital Universitario de Torrej\u00f3n  Madrid Spain"},{"name":"School of Medicine, Faculty of Health Sciences Francisco de Vitoria University  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Fern\u00e1ndez\u2010Buhigas","sequence":"additional","affiliation":[{"name":"Fetal Medicine Department Hospital Universitario de Torrej\u00f3n  Madrid Spain"},{"name":"School of Medicine, Faculty of Health Sciences Francisco de Vitoria University  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Martin\u2010Arias","sequence":"additional","affiliation":[{"name":"Fetal Medicine Department Hospital Universitario de Torrej\u00f3n  Madrid Spain"},{"name":"School of Medicine, Faculty of Health Sciences Francisco de Vitoria University  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Vargas\u2010Terrones","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias del Deporte INEF Universidad Polit\u00e9cnica de Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Barakat","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias del Deporte INEF Universidad Polit\u00e9cnica de Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Santacruz","sequence":"additional","affiliation":[{"name":"Fetal Medicine Department Hospital Universitario de Torrej\u00f3n  Madrid Spain"},{"name":"School of Medicine, Faculty of Health Sciences Francisco de Vitoria University  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,2]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.906081"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318278f56a"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2012.03.010"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2012.11.020"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31828aea03"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1271211"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181cfce4f"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31824758e0"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.114.094946"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2047-6310.2012.00110.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.11.039"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-016-1121-7"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/GRF.0000000000000212"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2012.05.011"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001214"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12371"},{"key":"e_1_2_5_18_1","unstructured":"Ministerio de Sanidad Servicios Sociales e Igualdad. Gu\u00eda de pr\u00e1ctica cl\u00ednica de atenci\u00f3n en el embarazo y puerperio.2014.https:\/\/www.mscbs.gob.es\/organizacion\/sns\/planCalidadSNS\/pdf\/Guia_practica_AEP.pdf"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1159\/000330792"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2005.10.029"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.81.3.229"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.57.6.528"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2000.00160.x"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/GCO.0b013e328332d24e"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02801.x"},{"key":"e_1_2_5_26_1","first-page":"CD007145","article-title":"Diet or exercise, or both, for preventing excessive weight gain in pregnancy","author":"Muktabhant B","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2013.07.020"},{"key":"e_1_2_5_28_1","first-page":"21","article-title":"Efecto de un programa de ejercicio f\u00edsico en la recuperaci\u00f3n post\u2010parto","volume":"30","author":"Barakat R","year":"2013","journal-title":"Arch Med Deporte"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/3-540-28903-8_37"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199311183292111"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1159\/000092870"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.2647"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1038"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-200306000-00025"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(03)00176-3"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2010.06.006"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1159\/000338003"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(02)02953-3"},{"key":"e_1_2_5_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2017-098245"}],"updated-by":[{"DOI":"10.1002\/uog.24831","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T00:00:00Z","timestamp":1640822400000}}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.20147","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.20147","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/uog.20147","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.20147","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T21:59:04Z","timestamp":1694383144000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.20147"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,2]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1002\/uog.20147"],"URL":"https:\/\/doi.org\/10.1002\/uog.20147","archive":["Portico"],"relation":{"correction":[{"id-type":"doi","id":"10.1002\/uog.24831","asserted-by":"object"}]},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,2]]},"assertion":[{"value":"2018-05-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}