{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:18:40Z","timestamp":1777695520649,"version":"3.51.4"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005413","name":"Universit\u00e9 Paris Descartes","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005413","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Incompatibility between currently available fetoscopes and the anatomical constraints of the distended fetal bladder, with the resulting curvature around the bladder neck, account for most technical difficulties during fetal cystoscopy in lower urinary tract obstruction (LUTO). The aim of this anatomical study was to assess by magnetic resonance imaging (MRI) the variation in three bladder angles (bladder\u2010neck angle (BNA), vesicourethral angle (VUA) and angle between bladder dome and posterior urethra (DUA)), according to gestational age (GA), bladder volume and the presence of \nLUTO.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From our fetal medicine database, we retrieved for review 46 MRI examinations of male fetuses between 2015 and 2019, including 17 with LUTO, examined at a mean GA of 28.1 (range, 17.3\u201335.0)\u2009weeks and 29 age\u2010matched controls, examined at 29.9 (range, 21.9\u201335.0)\u2009weeks. We measured bladder volume, bladder\u2010wall thickness and the three bladder angles, and used the Mann\u2013Whitney <jats:italic>U<\/jats:italic>\u2010test to compare values between groups. Variations according to GA and bladder volume were determined using analysis of variance (ANOVA). A reliability study was performed using the Bland\u2013Altman method and Lin's correlation coefficient was calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both bladder volume and bladder\u2010wall thickness were significantly greater in the LUTO group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). BNA was significantly larger in LUTO compared with control fetuses: the mean (range) was 127.1\u00b0 (101.6\u2013161.6\u00b0) <jats:italic>vs<\/jats:italic> 111.2\u00b0 (88.5\u2013157.3\u00b0) (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). DUA averaged 117\u00b0 and showed no difference between the groups (<jats:italic>P<\/jats:italic>\u2009=\u20090.92). No statistical comparison was performed on VUA since this was not measurable in most control fetuses. ANOVA showed no variation of any angle with bladder volume in both LUTO fetuses and control fetuses. BNA in LUTO fetuses was the only angle to vary with GA, being larger after, compared with at or before, 25\u2009weeks (<jats:italic>P<\/jats:italic>\u2009=\u20090.04). The reliability study showed an acceptable bias for both intra\u2010 and interobserver reproducibility for all three angles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The findings that BNA is increased by approximately 15\u00b0 in fetuses with LUTO and DUA averages 117\u00b0 could aid in development of a customized fetal cystoscope and help to overcome the current technical challenges of fetal cystoscopy. Copyright \u00a9 2019 ISUOG. Published by John Wiley &amp; Sons Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.20297","type":"journal-article","created":{"date-parts":[[2019,4,22]],"date-time":"2019-04-22T07:18:47Z","timestamp":1555917527000},"page":"86-95","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Biometric and morphological features on magnetic resonance imaging of fetal bladder in lower urinary tract obstruction: new perspectives for fetal cystoscopy"],"prefix":"10.1002","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2453-9620","authenticated-orcid":false,"given":"N.","family":"Vinit","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery and Urology Necker\u2010Enfants Malades Hospital, APHP  Paris France"},{"name":"EA 7328\u2010PACT, Paris Descartes University Sorbonne Paris Cit\u00e9, Imagine Institue  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Grevent","sequence":"additional","affiliation":[{"name":"EA 7328\u2010PACT, Paris Descartes University Sorbonne Paris Cit\u00e9, Imagine Institue  Paris France"},{"name":"Department of Pediatric Radiology Necker\u2010Enfants Malades Hospital, APHP  Paris France"},{"name":"INSERM U1000 and UMR1163 Imagine Institute  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.\u2010E.","family":"Millischer\u2010Bellaiche","sequence":"additional","affiliation":[{"name":"EA 7328\u2010PACT, Paris Descartes University Sorbonne Paris Cit\u00e9, Imagine Institue  Paris France"},{"name":"Department of Pediatric Radiology Necker\u2010Enfants Malades Hospital, APHP  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. M.","family":"Pandya","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Fetal Medicine and Surgery Necker\u2010Enfants Malades Hospital, APHP  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Sonigo","sequence":"additional","affiliation":[{"name":"EA 7328\u2010PACT, Paris Descartes University Sorbonne Paris Cit\u00e9, Imagine Institue  Paris France"},{"name":"Department of Pediatric Radiology Necker\u2010Enfants Malades Hospital, APHP  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Delmonte","sequence":"additional","affiliation":[{"name":"IMAG2 Laboratory Imagine Institute  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Sarnacki","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Urology Necker\u2010Enfants Malades Hospital, APHP  Paris France"},{"name":"IMAG2 Laboratory Imagine Institute  Paris France"},{"name":"Paris Descartes University Sorbonne Paris Cit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Aigrain","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Urology Necker\u2010Enfants Malades Hospital, APHP  Paris France"},{"name":"Paris Descartes University Sorbonne Paris Cit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Boddaert","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology Necker\u2010Enfants Malades Hospital, APHP  Paris France"},{"name":"INSERM U1000 and UMR1163 Imagine Institute  Paris France"},{"name":"Paris Descartes University Sorbonne Paris Cit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Bessi\u00e8res","sequence":"additional","affiliation":[{"name":"Department of Histology, Embryology and Cytogenetics Necker\u2010Enfants Malades Hospital, APHP  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Benchimol","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Fetal Medicine and Surgery Necker\u2010Enfants Malades Hospital, APHP  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. J.","family":"Salomon","sequence":"additional","affiliation":[{"name":"EA 7328\u2010PACT, Paris Descartes University Sorbonne Paris Cit\u00e9, Imagine Institue  Paris France"},{"name":"Department of Obstetrics, Fetal Medicine and Surgery Necker\u2010Enfants Malades Hospital, APHP  Paris France"},{"name":"Paris Descartes University Sorbonne Paris Cit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. J.","family":"Stirnemann","sequence":"additional","affiliation":[{"name":"EA 7328\u2010PACT, Paris Descartes University Sorbonne Paris Cit\u00e9, Imagine Institue  Paris France"},{"name":"Department of Obstetrics, Fetal Medicine and Surgery Necker\u2010Enfants Malades Hospital, APHP  Paris France"},{"name":"Paris Descartes University Sorbonne Paris Cit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Blanc","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Urology Necker\u2010Enfants Malades Hospital, APHP  Paris France"},{"name":"EA 7328\u2010PACT, Paris Descartes University Sorbonne Paris Cit\u00e9, Imagine Institue  Paris France"},{"name":"Paris Descartes University Sorbonne Paris Cit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5675-267X","authenticated-orcid":false,"given":"Y.","family":"Ville","sequence":"additional","affiliation":[{"name":"EA 7328\u2010PACT, Paris Descartes University Sorbonne Paris Cit\u00e9, Imagine Institue  Paris France"},{"name":"Department of Obstetrics, Fetal Medicine and Surgery Necker\u2010Enfants Malades Hospital, APHP  Paris France"},{"name":"Paris Descartes University Sorbonne Paris Cit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91381-5"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.717"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2418"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.5603\/GP.a2017.0048"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.13405"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2736"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.18990"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2012.05.001"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90837-8"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(19980115)17:1<101::AID-SIM727>3.0.CO;2-E"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.2350\/13-08-1359-OA.1"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000351030"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5188"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.20297","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.20297","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/uog.20297","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.20297","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T06:19:41Z","timestamp":1693894781000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.20297"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1002\/uog.20297"],"URL":"https:\/\/doi.org\/10.1002\/uog.20297","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"2019-02-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}