{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T21:39:49Z","timestamp":1757540389886,"version":"3.40.5"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the association between preterm birth and cervical length after arrested preterm labor in high\u2010risk pregnant women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this <jats:italic>post\u2010hoc<\/jats:italic> analysis of a randomized clinical trial, transvaginal cervical length was measured in women whose contractions had ceased 48\u2009h after admission for threatened preterm labor. At admission, women were defined as having a high risk of preterm birth based on a cervical length of &lt;\u200915\u2009mm or a cervical length of 15\u201330\u2009mm with a positive fetal fibronectin test. Logistic regression analysis was used to investigate the association of cervical length measured at least 48\u2009h after admission and of the change in cervical length between admission and at least 48\u2009h later, with preterm birth before 34\u2009weeks' gestation and delivery within 7\u2009days after admission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 164 women were included in the analysis. Women whose cervical length increased between admission for threatened preterm labor and 48\u2009h later (32%; <jats:italic>n<\/jats:italic>\u2009=\u200953) were found to have a lower risk of preterm birth before 34\u2009weeks compared with women whose cervical length did not change (adjusted odds ratio (aOR), 0.24 (95%\u2009CI, 0.09\u20130.69)). The risk in women with a decrease in cervical length between the two timepoints was not different from that in women with no change in cervical length (aOR, 1.45 (95%\u2009CI, 0.62\u20133.41)). Moreover, greater absolute cervical length after 48\u2009h was associated with a lower risk of preterm birth before 34\u2009weeks (aOR, 0.90 (95%\u2009CI, 0.84\u20130.96)) and delivery within 7\u2009days after admission (aOR, 0.91 (95%\u2009CI, 0.82\u20131.02)). Sensitivity analysis in women randomized to receive no intervention showed comparable results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study suggests that the risk of preterm birth before 34\u2009weeks is lower in women whose cervical length increases between admission for threatened preterm labor and at least 48\u2009h later when contractions had ceased compared with women in whom cervical length does not change or decreases. \u00a9 2021 The Authors. 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A.","family":"de Boer","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Amsterdam Reproduction &amp; Development Research Institute, Amsterdam UMC, Vrije Universiteit  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sueters","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Leiden University Medical Center  Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. C. J.","family":"Scheepers","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Maastricht University Medical Center  Maastricht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. T. 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