{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T17:53:32Z","timestamp":1789494812487,"version":"build-2803163510"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To examine the impact of first\u2010trimester crown\u2013rump length (CRL) measurement error on the interpretation of estimated fetal weight (EFW) and classification of fetuses as small\u2010, large\u2010 or appropriate\u2010for\u2010gestational age on subsequent growth scans.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We examined the effects of errors of \u00b1\u20092, \u00b1\u20093 and \u00b1\u20094\u2009mm in the measurement of fetal CRL on percentiles of EFW at 20, 32 and 36\u2009weeks' gestation and classification as small\u2010, large\u2010 or appropriate\u2010for\u2010gestational age. Published data on CRL measurement error were used to determine variation present in practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A measurement error of \u22122\u2009mm in first\u2010trimester CRL shifts an EFW on the 10<jats:sup>th<\/jats:sup> percentile at the 20\u2010week scan to around the 20<jats:sup>th<\/jats:sup> percentile, and the effect of a CRL measurement error of +\u20092\u2009mm would shift an EFW on the 10<jats:sup>th<\/jats:sup> percentile to around the 5<jats:sup>th<\/jats:sup> percentile. At 32\u2009weeks, a first\u2010trimester CRL measurement error would shift an EFW on the 10<jats:sup>th<\/jats:sup> percentile to the 7<jats:sup>th<\/jats:sup> (+\u20092\u2009mm) or 14<jats:sup>th<\/jats:sup> (\u22122\u2009mm) percentile; at 36\u2009weeks, the EFW would shift from the 10<jats:sup>th<\/jats:sup> percentile to the 8<jats:sup>th<\/jats:sup> (+\u20092\u2009mm) or 12<jats:sup>th<\/jats:sup> (\u22122\u2009mm) percentile. Published data suggest that measurement errors of 2\u2009mm or more are common in practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Because of the widespread and potentially severe consequences of CRL measurement errors as small as 2\u2009mm on clinical assessment, patient management and research results, there is a need to increase awareness of the impact of CRL measurement error and to reduce measurement error variation through standardization and quality control. \u00a9 2021 International Society of Ultrasound in Obstetrics and Gynecology.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.23690","type":"journal-article","created":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T06:59:12Z","timestamp":1621234752000},"page":"354-359","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Crown\u2013rump length measurement error: impact on assessment of growth"],"prefix":"10.1002","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1331-3503","authenticated-orcid":false,"given":"K.","family":"Gadsb\u00f8ll","sequence":"first","affiliation":[{"name":"Center for Fetal Medicine, Pregnancy and Ultrasound, Department of Obstetrics Copenhagen University Hospital, Rigshospitalet  Copenhagen Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Wright","sequence":"additional","affiliation":[{"name":"Institute of Health Research University of Exeter  Exeter UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4633-4738","authenticated-orcid":false,"given":"S. E.","family":"Kristensen","sequence":"additional","affiliation":[{"name":"Center for Fetal Medicine, Pregnancy and Ultrasound, Department of Obstetrics Copenhagen University Hospital, Rigshospitalet  Copenhagen Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7686-9509","authenticated-orcid":false,"given":"V.","family":"Verfaille","sequence":"additional","affiliation":[{"name":"Ultrasound Clinic BovenMaas  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1266-0711","authenticated-orcid":false,"given":"K. 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