{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T04:59:11Z","timestamp":1787461151195,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,2,8]],"date-time":"2022-02-08T00:00:00Z","timestamp":1644278400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2019\/01280\u20103"],"award-info":[{"award-number":["2019\/01280\u20103"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Hypertensive disorders of pregnancy (HDP) are associated with significant myocardial dysfunction on echocardiography. The impact of hemodynamic changes related to volume redistribution following delivery on myocardial function in women with HDP has not been evaluated systematically. The aim of this study was to compare echocardiographic findings immediately before and after delivery in women with HDP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a prospective longitudinal study including 30 women with a diagnosis of HDP who underwent two consecutive transthoracic echocardiographic (TTE) examinations, before delivery and in the early postpartum period. Paired comparisons of the findings from the two assessments were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Left\u2010ventricular (LV) concentric remodeling or hypertrophy was detected in 21 (70%) patients. There was no significant difference in cardiac morphology indices such as LV mass index (78.9\u2009\u00b1\u200916.3\u2009g\/m<jats:sup>2<\/jats:sup> <jats:italic>vs<\/jats:italic> 77.9\u2009\u00b1\u200915.4\u2009g\/m<jats:sup>2<\/jats:sup>; <jats:italic>P<\/jats:italic>\u2009=\u20090.611) or relative wall thickness (0.45\u2009\u00b1\u20090.1 <jats:italic>vs<\/jats:italic> 0.44\u2009\u00b1\u20090.1; <jats:italic>P<\/jats:italic>\u2009=\u20090.453) before <jats:italic>vs<\/jats:italic> after delivery. LV diastolic function did not demonstrate any peripartum variation, with similar left\u2010atrial volume (52.4\u2009\u00b1\u200915.3\u2009mL <jats:italic>vs<\/jats:italic> 51.0\u2009\u00b1\u200915.6\u2009mL; <jats:italic>P<\/jats:italic>\u2009=\u20090.433), lateral E\u2032 (0.12\u2009\u00b1\u20090.03\u2009m\/s <jats:italic>vs<\/jats:italic> 0.12\u2009\u00b1\u20090.03\u2009m\/s; <jats:italic>P<\/jats:italic>\u2009=\u20090.307) and E\/E\u2032 ratio (7.9\u2009\u00b1\u20092.2 <jats:italic>vs<\/jats:italic> 7.9\u2009\u00b1\u20091.7; <jats:italic>P<\/jats:italic>\u2009=\u20090.934) before <jats:italic>vs<\/jats:italic> after delivery. Systolic function indices, such as LV ejection fraction (57.5\u2009\u00b1\u20093.4% <jats:italic>vs<\/jats:italic> 56.4\u2009\u00b1\u20092.1%; <jats:italic>P<\/jats:italic>\u2009=\u20090.295) and global longitudinal strain (\u221215.3\u2009\u00b1\u20092.6% <jats:italic>vs<\/jats:italic>\u00a0\u221215.1\u2009\u00b1\u20093.1%; <jats:italic>P<\/jats:italic>\u2009=\u20090.582), also remained unchanged between before <jats:italic>vs<\/jats:italic> after delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Maternal hemodynamic changes associated with delivery did not influence significantly peripartum TTE indices in women with HDP. Suboptimal maternal echocardiographic findings in HDP are likely to be the consequence of chronic pregnancy cardiovascular load changes or pre\u2010existing maternal cardiovascular impairment. Severity and persistence of myocardial dysfunction in the postpartum period may be related to the long\u2010term maternal cardiovascular disease legacy of HDP. \u00a9 2021 The Authors. <jats:italic>Ultrasound in Obstetrics &amp; Gynecology<\/jats:italic> published by John Wiley &amp; Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.23745","type":"journal-article","created":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T14:44:11Z","timestamp":1627310651000},"page":"365-370","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Peripartum echocardiographic changes in women with hypertensive disorders of pregnancy"],"prefix":"10.1002","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3991-9308","authenticated-orcid":false,"given":"V.","family":"Giorgione","sequence":"first","affiliation":[{"name":"Vascular Biology Research Center, Molecular and Clinical Sciences Research Institute, St George's University of London  London UK"},{"name":"Fetal Medicine Unit St George's University Hospitals NHS Foundation Trust, University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"O'Driscoll","sequence":"additional","affiliation":[{"name":"Department of Cardiology St George's University Hospitals NHS Foundation Trust  London UK"},{"name":"School of Psychology and Life Sciences, Canterbury Christ Church University  Canterbury UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1966-0466","authenticated-orcid":false,"given":"C. M.","family":"Coutinho","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit St George's University Hospitals NHS Foundation Trust, University of London  London UK"},{"name":"Department of Gynecology and Obstetrics Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo  Ribeir\u00e3o Preto S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Di Fabrizio","sequence":"additional","affiliation":[{"name":"Vascular Biology Research Center, Molecular and Clinical Sciences Research Institute, St George's University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Cardiology St George's University Hospitals NHS Foundation Trust  London 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