{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T10:49:12Z","timestamp":1772794152129,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the short\u2010 and long\u2010term outcome of late\u2010preterm compared with term birth in twin pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective observational cohort study included all women who had a twin delivery between 1 January 2007 and 31 December 2010 recorded in the claims database of the Korea National Health Insurance, with at least one follow\u2010up recorded in the database of the National Health Screening Program for Infants and Children. Outcomes were analyzed at the pregnancy level, with adverse outcome being defined as an adverse outcome in one or both twins, identified by a diagnosis according to the International Classification of Diseases 10<jats:sup>th<\/jats:sup> Revision. The primary short\u2010term outcome was composite morbidity, which included any of the following: transient tachypnea, respiratory distress syndrome, necrotizing enterocolitis, intraventricular hemorrhage and bronchopulmonary dysplasia. Long\u2010term adverse outcome included any neurological or neurodevelopmental outcome, defined by prespecified neurological and developmental diagnoses; these were assessed by following up all neonates until the end of 2018, by which time they were 8\u201311\u2009years of age. Outcomes were compared between twins delivered late preterm (34\u2009+\u20090 to 36\u2009+\u20096\u2009weeks) and those delivered at term (\u2265\u200937\u2009weeks).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 17\u2009189 women who delivered twins at \u2265\u200934\u2009weeks of gestation during the study period, 5032 (29.27%) women delivered in the late\u2010preterm period. On multivariate analysis, compared with the twins delivered at term, the late\u2010preterm twins had an increased risk for the primary short\u2010term outcome of composite morbidity (adjusted odds ratio (aOR), 2.09; 95%\u2009CI, 1.90\u20132.30), including transient tachypnea (aOR, 1.85; 95%\u2009CI, 1.64\u20132.09), respiratory distress syndrome (aOR, 2.31; 95%\u2009CI, 2.04\u20132.62), necrotizing enterocolitis (aOR, 2.10; 95%\u2009CI, 1.20\u20133.69) and intraventricular hemorrhage (aOR, 2.13; 95%\u2009CI, 1.46\u20133.11). For the long\u2010term outcome, the late\u2010preterm twins also had an increased risk for any neurological or neurodevelopmental outcome (adjusted hazard ratio, 1.14; 95%\u2009CI, 1.07\u20131.21).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Twins delivered in the late\u2010preterm period have an increased risk for short\u2010 and long\u2010term morbidity compared with twins delivered at term. These results should be considered when determining the timing of delivery in uncomplicated twin pregnancy. \u00a9 2021 International Society of Ultrasound in Obstetrics and Gynecology.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.24838","type":"journal-article","created":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T12:39:34Z","timestamp":1640090374000},"page":"763-770","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Short\u2010term neonatal and long\u2010term infant outcome of late\u2010preterm twins: nationwide population\u2010based study"],"prefix":"10.1002","volume":"59","author":[{"given":"G. J.","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Korea University Guro Hospital, Korea University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.\u2010D.","family":"Cho","sequence":"additional","affiliation":[{"name":"Big Data Department National Health Insurance Service  Gangwon\u2010do Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6469-8140","authenticated-orcid":false,"given":"H. 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