{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T02:50:45Z","timestamp":1787626245215,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,4,7]],"date-time":"2023-04-07T00:00:00Z","timestamp":1680825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare the prevalence of preterm birth (PTB) (delivery before 37\u2009weeks) in Israel before and after publication of national guidelines recommending second\u2010trimester sonographic cervical\u2010length (CL) measurement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Israeli Society of Obstetrics and Gynecology (ISOG) guidelines, issued on 1 January 2012, specified that CL should be measured transabdominally or, if this is not possible, transvaginally, at the 19\u201325\u2010week ultrasound anomaly scan and that CL &lt;\u200925\u2009mm should indicate further work\u2010up and treatment, although the type of treatment was unspecified. In 2000, the Israel Ministry of Health issued a legal requirement for the submission of delivery records to a national registry. These data were used to compare PTB prevalence in the period before (2000\u20132011) and that after (2012\u20132020) publication of the guidelines, as well as trends within each time period. Information was available on singleton and multiple pregnancy and maternal age and parity, as well as low birth weight (&lt;\u20092500\u2009g).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      During the period 2000\u20132020, there were 3\u2009403\u2009976 infants liveborn in Israel: 1\u2009797\u2009657 before and 1\u2009606\u2009319 after publication of the ISOG guidelines. There were 247\u2009187 PTBs overall, with a prevalence of 7.64% (95%\u2009CI, 7.52\u20137.77%) before publication of the guidelines and 6.84% (95%\u2009CI, 6.43\u20137.24%) afterwards (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.0002, two\u2010tailed). The annual PTB prevalence was static in the first time period but declined by 0.18% per annum during the second period, after publication of the guidelines. The proportionate reduction in PTB prevalence after compared with before publication of the guidelines was 10% overall, 9% for PTB at 33\u201336\u2009weeks, 18% for PTB at 28\u201332\u2009weeks and 24% for PTB at &lt;\u200928\u2009weeks. After publication of the guidelines, reduced prevalence of PTB was observed among singletons (5.49% before\n                      <jats:italic>vs<\/jats:italic>\n                      4.83% after,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.0001), but not among infants in twin or higher\u2010order multiple pregnancy. There was a statistically significant reduction in the rate of PTB following publication of the guidelines in both nulliparous and parous women and in the 19\u201339\u2010year\u2010old maternal\u2010age group. Although reductions in PTB prevalence were also noted in high\u2010risk age groups (maternal age &lt;\u200919\u2009years and \u2265\u200940\u2009years), these did not reach statistical significance. Following publication of the guidelines, there was a statistically significant reduction in the prevalence of birth weight under 2500\u2009g, of a magnitude similar to that for PTB prevalence.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The publication of national guidelines recommending routine CL measurement at the time of the second\u2010trimester anomaly scan was associated with a fall in PTB prevalence in singleton pregnancies. Whilst direct evidence linking screening with this fall in prevalence is lacking, it is likely that implementation of routine CL screening played an important role in the reduction of PTB rate. Our experience indicates that screening can be incorporated into the second\u2010trimester anomaly scan. \u00a9 2022 International Society of Ultrasound in Obstetrics and Gynecology.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/uog.26093","type":"journal-article","created":{"date-parts":[[2022,10,7]],"date-time":"2022-10-07T17:18:30Z","timestamp":1665163110000},"page":"610-616","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Change in prevalence of preterm birth in Israel following publication of national guidelines recommending routine sonographic cervical\u2010length measurement at 19\u201325 weeks' gestation"],"prefix":"10.1002","volume":"61","author":[{"given":"R.","family":"Maymon","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Shamir (Assaf Harofeh) Medical Center  Zerifin Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Pekar\u2010Zlotin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Shamir (Assaf Harofeh) Medical Center  Zerifin Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Meiri","sequence":"additional","affiliation":[{"name":"PreTwin Screen Consortium and TeleMarpe Ltd  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Haklai","sequence":"additional","affiliation":[{"name":"Health Information Division Israel Ministry of Health  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.\u2010S.","family":"Gordon","sequence":"additional","affiliation":[{"name":"Health Information Division Israel Ministry of Health  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Shlichkov","sequence":"additional","affiliation":[{"name":"Health Information Division Israel Ministry of Health  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2450-2403","authenticated-orcid":false,"given":"H.","family":"Cuckle","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60560-1"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60074-4"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2018.03.028"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13835"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13837"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199602293340904"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-200312000-00026"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5174"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.9073"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.14392"},{"key":"e_1_2_7_12_1","unstructured":"UK National Screening Committee.Screening in the UK: making effective recommendations 1 April 2020 to 31 March 2021. 1.16\u2009Preterm birth in low risk women.https:\/\/view\u2010health\u2010screening\u2010recommendations.service.gov.uk\/preterm\u2010birth\/."},{"key":"e_1_2_7_13_1","unstructured":"Israeli Society of Obstetrics and Gynecology.Position paper 8: Guidelines for performing an ultrasound during pregnancy.https:\/\/cdn.mednet.co.il\/2017\/01\/%D7%A0%D7%99%D7%99%D7%A8\u2010%D7%A2%D7%9E%D7%93%D7%94\u2010%D7%9E%D7%A2%D7%95%D7%93%D7%9B%D7%9F\u20108.pdf"},{"key":"e_1_2_7_14_1","unstructured":"Israel Ministry of Health.Live births in Israel.https:\/\/www.gov.il\/BlobFolder\/reports\/live\u2010birth\u2010in\u2010israel\/he\/files_publications_units_info_birth_2000_2017.pdf"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1704559"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2871"},{"key":"e_1_2_7_17_1","unstructured":"YankoA.Negligence claims in Israel: this is the department that is sued the most.August 2022.https:\/\/www.ynet.co.il\/health\/article\/sym11gjfji."},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057108"},{"issue":"365","key":"e_1_2_7_19_1","first-page":"e1","article-title":"A universal mid\u2010trimester transvaginal cervical length screening program and its associated reduced preterm birth rate","volume":"214","author":"Son M","year":"2016","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.11.1037"},{"issue":"219","key":"e_1_2_7_21_1","first-page":"e1","article-title":"The introduction of a universal transvaginal cervical length screening program is associated with a reduced preterm birth rate","volume":"228","author":"Figarella A","year":"2023","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_7_22_1","article-title":"The Israeli Society for Fetal Medicine and The Israeli Association of Obstetrics and Gynecology","author":"Yanon Y","journal-title":"The treatment of premature birth and its prevention."},{"issue":"86","key":"e_1_2_7_23_1","first-page":"e1","article-title":"Early vaginal progesterone versus placebo in twin pregnancies for the prevention of spontaneous preterm birth: a randomized, double\u2010blind trial","volume":"224","author":"Rehal A","year":"2021","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2016.1268595"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.12.004"},{"issue":"554","key":"e_1_2_7_26_1","first-page":"e1","article-title":"Cost\u2010effectiveness of transvaginal ultrasound cervical length screening in singletons without a prior preterm birth: an update","volume":"213","author":"Werner EF","year":"2015","journal-title":"Am J Obstet Gynecol"},{"issue":"100","key":"e_1_2_7_27_1","first-page":"e1","article-title":"Cost\u2010effectiveness of risk\u2010based screening for cervical length to prevent preterm birth","volume":"215","author":"Einerson BD","year":"2016","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13021"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.24884"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.26020"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.26093","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.26093","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T16:02:34Z","timestamp":1692460954000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.26093"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,7]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1002\/uog.26093"],"URL":"https:\/\/doi.org\/10.1002\/uog.26093","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,7]]},"assertion":[{"value":"2022-06-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}