{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:23:19Z","timestamp":1790018599832,"version":"4.0.1"},"reference-count":47,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,3,2]],"date-time":"2006-03-02T00:00:00Z","timestamp":1141257600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2006,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the role of conservative management in the treatment of cervical ectopic pregnancies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective analysis of all cervical ectopic pregnancies diagnosed in women attending our early pregnancy unit between April 1997 and September 2004 inclusive. The diagnosis of cervical ectopic pregnancy was made using transvaginal ultrasound. Clinical and demographic data were recorded in all cases. Serum human chorionic gonadotropin levels were measured at presentation and monitored subsequently to determine the rate of successful resolution. Conservative management was in the form of medical or expectant management. Medical management involved administration of systemic or intra\u2010amniotic methotrexate, with or without intra\u2010amniotic potassium chloride. Systemic methotrexate was either a single dose of 50 mg\/m<jats:sup>2<\/jats:sup> or an alternate\u2010day regimen of methotrexate at 1 mg\/kg (days 1,3,5) with folinic acid rescue (days 2,4,6). If intra\u2010amniotic treatment was required, this was either 50 mg methotrexate or 5 mmol\/L potassium chloride.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seven cervical ectopic pregnancies were diagnosed during the study period. Three cases were managed successfully with a single dose of methotrexate. One case was managed successfully using a multiple\u2010dose methotrexate regimen. Another case failed medical management with both the single\u2010 and multiple\u2010dose regimens but was successfully treated after potassium chloride was given intra\u2010amniotically under ultrasound guidance. One case was successfully treated with intra\u2010amniotic methotrexate and another was managed expectantly. There was no associated morbidity or mortality during the study period. We also performed a review of the current literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The conservative management of cervical ectopic pregnancy is effective and safe. Copyright \u00a9 2006 ISUOG. 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