{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T09:59:01Z","timestamp":1769075941925,"version":"3.49.0"},"reference-count":67,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T00:00:00Z","timestamp":1728518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Enhanced recovery after surgery (ERAS) protocols are multimodal evidence\u2010based care plans that have been adopted for multiple surgical procedures to promote faster and better patient recovery and shorter hospitalization. This study aimed to explore whether worldwide fetal therapy centers offering prenatal myelomeningocele repair implement the ERAS principles and to provide recommendations for improved perioperative management of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this survey study, a total of 53 fetal therapy centers offering prenatal surgery for open spina bifida were identified and invited to complete a digital questionnaire covering their pre\u2010, intra\u2010 and postoperative management. An overall score was calculated per center based on compliance with 20 key ERAS principles, extrapolated from ERAS guidelines for Cesarean section, gynecological oncology and colorectal surgery. Each item was awarded a score of 1 or 0, depending, respectively, on whether the center did or did not comply with that principle, with a maximum score of 20.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The questionnaire was completed by 46 centers in 17 countries (response rate, 87%). In total, 22 (48%) centers performed exclusively open fetal surgery (laparotomy and hysterotomy), whereas 14 (30%) offered both open and fetoscopic procedures and 10 (22%) used only fetoscopy. The perioperative management of patients undergoing fetoscopic and open surgery was very similar. The median ERAS score was 12 (range, 8\u201317), with a mean\u2009\u00b1\u2009SD of 12.5\u2009\u00b1\u20092.4. Center compliance was the highest for the use of regional anesthesia (98%), avoidance of bowel preparation (96%) and thromboprophylaxis (96%), while the lowest compliance was observed for preoperative carbohydrate loading (15%), a 2\u2010h fasting period for clear fluids (20%), postoperative nausea and vomiting prevention (33%) and early feeding (35%). ERAS scores were similar in centers with a short (2\u20135\u2009days), medium (6\u201310\u2009days) and long (\u2265\u200911\u2009days) hospital stay (mean\u2009\u00b1\u2009SD, 12.9\u2009\u00b1\u20092.4, 12.1\u2009\u00b1\u20092.0 and 10.3\u2009\u00b1\u20093.2, respectively, <jats:italic>P<\/jats:italic>\u2009=\u20090.15). Furthermore, there was no significant association between ERAS score and surgical technique or case volume.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The perioperative management of fetal spina bifida surgery is highly variable across fetal therapy centers worldwide. Standardized protocols integrating ERAS principles may improve patient recovery, reduce maternal morbidity and shorten the hospital stay after fetal spina bifida surgery. \u00a9 2024 The Author(s). <jats:italic>Ultrasound in Obstetrics &amp; Gynecology<\/jats:italic> published by John Wiley &amp; Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.27701","type":"journal-article","created":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T04:55:05Z","timestamp":1716180905000},"page":"669-677","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Enhanced recovery after fetal spina bifida surgery: global practice"],"prefix":"10.1002","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6718-1454","authenticated-orcid":false,"given":"K.","family":"Nulens","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Division of Maternal\u2013Fetal Medicine Mount Sinai Hospital and University of Toronto  Toronto ON Canada"},{"name":"Department of Biomedical Sciences University of Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7388-1414","authenticated-orcid":false,"given":"Y.","family":"Kunpalin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Division of Maternal\u2013Fetal Medicine Mount Sinai Hospital and University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Nijs","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences University of Leuven  Leuven Belgium"},{"name":"Department of Anesthesiology and Pain Medicine University Health Network and University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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