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Conservative management with single\u2010dose methotrexate was undertaken, but owing to the failure of human chorionic gonadotropin (hCG) levels to fall by 15% by day 7 and the persistence of fetal cardiac activity, two further doses of methotrexate were required. The patient's hCG levels were monitored, and repeat transvaginal ultrasonography was performed until complete resolution of the pregnancy by spontaneous miscarriage. We describe the ultrasonographic findings, which showed that the sac size increased despite treatment. Copyright \u00a9 2006 ISUOG. Published by John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/uog.3846","type":"journal-article","created":{"date-parts":[[2006,10,24]],"date-time":"2006-10-24T17:06:19Z","timestamp":1161709579000},"page":"845-847","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Ultrasonographic appearance of cervical pregnancy following successful treatment with methotrexate"],"prefix":"10.1002","volume":"28","author":[{"given":"O.","family":"Api","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Unal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Api","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Ergin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Alkan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Kars","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Turan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,24]]},"reference":[{"key":"e_1_2_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-200012000-00012"},{"key":"e_1_2_3_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archfami.9.1.72"},{"issue":"7","key":"e_1_2_3_4_2","first-page":"S101","article-title":"Ectopic pregnancy management: cervical and abdominal pregnancies","volume":"32","author":"Riethmuller D","year":"2003","journal-title":"J Gynecol Obstet Biol Reprod (Paris)"},{"key":"e_1_2_3_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-199401000-00025"},{"key":"e_1_2_3_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.2693"},{"key":"e_1_2_3_7_2","first-page":"406","article-title":"Serial endovaginal sonography of ectopic pregnancies treated with methotrexate","volume":"77","author":"Brown DL","year":"1991","journal-title":"Obstet Gynecol"},{"key":"e_1_2_3_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/17.10.2585"},{"key":"e_1_2_3_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-199903000-00006"},{"key":"e_1_2_3_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199912233412604"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.3846","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.3846","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T08:40:34Z","timestamp":1696668034000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.3846"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,24]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,11]]}},"alternative-id":["10.1002\/uog.3846"],"URL":"https:\/\/doi.org\/10.1002\/uog.3846","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,24]]},"assertion":[{"value":"2006-06-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2006-10-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}