{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T22:27:39Z","timestamp":1781908059607,"version":"3.54.5"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2007,4,30]],"date-time":"2007-04-30T00:00:00Z","timestamp":1177891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>At present little information is available to help define whether a certain degree of pelvic organ prolapse is clinically relevant. We performed a retrospective study to define cut\u2010offs for significant pelvic organ descent on the basis of prolapse symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>At a tertiary urogynecological center, 735 women with symptoms of lower urinary tract dysfunction and prolapse were seen for interview, clinical examination, multi\u2010channel urodynamics and ultrasound imaging, while supine and after voiding, for prolapse quantification. Women with multi\u2010compartment prolapse, i.e. those in whom no compartment was clearly dominant were excluded. Receiver\u2013operator statistics were used to test pelvic organ descent as a predictor of prolapse symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean age was 55.1 years, mean parity 2.8 (range, 0\u201312). Symptoms of prolapse were reported by 188 women (25.6%). Seventy\u2010four showed a symptomatic multi\u2010compartment prolapse and were excluded, 56 symptomatic women had cystoceles and 48 had rectoceles. Symptomatic cystoceles descended on average to 23.8 mm below the symphysis pubis and symptomatic rectoceles to 21.4 mm below the symphysis pubis. Descent was strongly associated with symptoms of prolapse (both, <jats:italic>P<\/jats:italic> &lt; 0.001). Receiver\u2013operating characteristics (ROC) statistics suggested a cut\u2010off of 10 mm below the symphysis pubis for cystocele, and 15 mm below the symphysis pubis for rectocele. ROC curves were similar for both compartments (area under the curve, 0.857 and 0.821, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Descent of the bladder to \u2265 10 mm and of the rectum to \u2265 15 mm below the symphysis pubis are strongly associated with symptoms, and these values are proposed as cut\u2010offs for the diagnosis of significant prolapse on the basis of ROC statistics. Copyright \u00a9 2007 ISUOG. Published by John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.4024","type":"journal-article","created":{"date-parts":[[2007,4,30]],"date-time":"2007-04-30T12:47:52Z","timestamp":1177937272000},"page":"688-691","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":115,"title":["Ultrasound assessment of pelvic organ prolapse: the relationship between prolapse severity and symptoms"],"prefix":"10.1002","volume":"29","author":[{"given":"H. P.","family":"Dietz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Lekskulchai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,4,30]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.01.025"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.125734"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70203-6"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.grf.0000170424.11993.73"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00568.x"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-196807000-00001"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.939"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001920200062"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1930"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2005.00486.x"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.12.004"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000180183.03897.72"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0960-7692.2001.00494.x"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70243-0"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.121897"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2001.tb01236.x"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2004.00428.x"},{"key":"e_1_2_5_19_2","unstructured":"OernoA DietzHP.Levator co\u2010activation is an important confounder of pelvic organ descent on Valsalva. 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