{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T05:09:03Z","timestamp":1793855343334,"version":"4.6.1"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate a classification of selective intrauterine growth restriction (sIUGR) in monochorionic (MC) twins based on the characteristics of umbilical artery (UA) Doppler flow in the smaller twin, in terms of association with clinical outcome and with the pattern of placental anastomoses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      One hundred and thirty\u2010four MC twins diagnosed with sIUGR at 18\u201326 weeks were classified as Type I (UA Doppler with positive diastolic flow,\n                      <jats:italic>n<\/jats:italic>\n                      = 39), Type II (persistent absent or reversed end\u2010diastolic flow,\n                      <jats:italic>n<\/jats:italic>\n                      = 30) and Type III (intermittent absent or reversed end\u2010diastolic flow,\n                      <jats:italic>n<\/jats:italic>\n                      = 65). Perinatal outcome, placental sharing and the pattern of anastomoses were compared with those in 76 uncomplicated MC twins.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean gestational age at delivery was 35.5 (range, 30\u201338) weeks in controls, 35.4 (range, 16\u201338) weeks in Type I, 30.7 (range, 27\u201340) weeks in Type II (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.0001) and 31.6 (range, 23\u201339) weeks in Type III (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.0001) pregnancies. Fetal weight discordance was significantly higher in Type II (38%) and Type III (36%) than in Type I (29%) (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.0001) pregnancies. Deterioration of the growth\u2010restricted fetus occurred in 90% of Type II cases, compared with 0% and 10.8% of Types I and III, respectively (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001). Unexpected intrauterine fetal death of the smaller twin occurred in 15.4% of Type III cases, compared with 2.6% and 0% of Types I and II respectively (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05). Parenchymal brain lesions in the larger twin were observed in 19.7% of Type III cases and less than 5% in the other groups (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05). Placental discordance (larger\/smaller) was 1.3 in controls, compared with 1.8, 2.6 and 4.4 in Types I, II and III, respectively (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.01). The proportion of cases with arterioarterial anastomoses &gt; 2 mm in diameter was 55% in controls, 70% in Type I, 18% in Type II (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.01) and 98% in Type III (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>sIUGR can be classified on the basis of umbilical artery Doppler into three types that correlate with different clinical behavior and different patterns of placental anastomoses. This classification may be of help in clinical decision\u2010making and when comparing clinical studies. Copyright \u00a9 2007 ISUOG. Published by John Wiley &amp; Sons, Ltd.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/uog.4046","type":"journal-article","created":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T07:46:57Z","timestamp":1180684017000},"page":"28-34","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":411,"title":["A classification system for selective intrauterine growth restriction in monochorionic pregnancies according to umbilical artery Doppler flow in the smaller twin"],"prefix":"10.1002","volume":"30","author":[{"given":"E.","family":"Gratac\u00f3s","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Lewi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Acosta\u2010Rojas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Hernandez\u2010Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. M.","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Carreras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Deprest","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,6,22]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-200304000-00013"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1997.tb10948.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.116724"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1105"},{"key":"e_1_2_6_6_2","first-page":"279","article-title":"Detecting fetal growth restriction or discordant growth in twin gestations stratified by placental chorionicity","volume":"49","author":"Chauhan SP","year":"2004","journal-title":"J Reprod Med"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1900"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(00)01111-X"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2003.07.004"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2004.06.016"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(00)70233-X"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2002.00749.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.215"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.256"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(94)90308-5"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0143-4004(03)00114-0"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1013"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)70344-8"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.2655"},{"key":"e_1_2_6_20_2","volume-title":"[Tablas espa\u00f1olas de pesos neonatales seg\u00fan edad gestacional.]","author":"Santamaria R","year":"1998"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.181.1.1887021"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(05)80189-5"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.08.062"},{"key":"e_1_2_6_24_2","first-page":"A76","article-title":"Placental sharing and birth weight in monochorionic twins: the critical role of \u2018life supporting\u2019 vascular anastomoses","volume":"13","author":"Lewi L","year":"2006","journal-title":"J Soc Gynecol Invest"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.133"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1080\/jmf.14.4.247.255"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/15.7.1632"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.4046","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.4046","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T04:01:32Z","timestamp":1696651292000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.4046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6,22]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["10.1002\/uog.4046"],"URL":"https:\/\/doi.org\/10.1002\/uog.4046","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6,22]]},"assertion":[{"value":"2007-03-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2007-06-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}