{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T07:00:25Z","timestamp":1772002825403,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2007,11,2]],"date-time":"2007-11-02T00:00:00Z","timestamp":1193961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2007,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the prevalence of hypertrophic cardiomyopathy\u2010like (HCL) changes in monochorionic twins with selective intrauterine growth restriction (sIUGR) and intermittent absent\/reversed end\u2010diastolic flow (iAREDF), also defined as Type III sIUGR, and the clinical relevance of this condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 80 pregnancies with sIUGR were studied, 40 with, and 40 without iAREDF. HCL changes were defined as an increased thickness of either left or right ventricular wall (mean &gt; 2 SD) estimated with M\u2010mode ultrasonography. Data were plotted on normal reference values constructed from 75 uncomplicated monochorionic twin pregnancies (150 fetuses) at 22\u201334 weeks' gestation. Perinatal outcomes in pregnancies with and without HCL changes were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the group with iAREDF, 8\/40 of the larger twins (20%) had HCL changes (five bilaterally, two in the right, and one in the left ventricle) as compared with 1\/40 (2.5%) in fetuses without iAREDF (<jats:italic>P<\/jats:italic> = 0.03). No differences were observed in the smaller twin (1\/40 in both groups). HCL changes were not associated with a significant increment in perinatal mortality as only one large fetus from the group with iAREDF died in utero. In the remaining 10 cases, no differences in the intertwin weight discordance, placental surface discordance, or rate of neonatal neurological damage were observed. However, all 10 presented mildly abnormal neonatal cardiac findings that resolved over time with no apparent short\u2010term impact on cardiac function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>HCL changes in the larger twin should be regarded as part of the spectrum of findings in Type III monochorionic\u2010sIUGR (presenting iAREDF). This finding does not seem to be associated with an increased rate of short\u2010term neurological or cardiac complications. Copyright \u00a9 2007 ISUOG. Published by John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.5166","type":"journal-article","created":{"date-parts":[[2007,11,2]],"date-time":"2007-11-02T12:17:43Z","timestamp":1194005863000},"page":"977-982","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Hypertrophic cardiomyopathy\u2010like changes in monochorionic twin pregnancies with selective intrauterine growth restriction and intermittent absent\/reversed end\u2010diastolic flow in the umbilical artery"],"prefix":"10.1002","volume":"30","author":[{"given":"B.","family":"Mu\u00f1oz\u2010Abellana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Hernandez\u2010Andrade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Figueroa\u2010Diesel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Q.","family":"Ferrer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Acosta\u2010Rojas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Cabero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Gratacos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,11,2]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-200304000-00013"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4046"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1013"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0143-4004(03)00114-0"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(94)90308-5"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1105"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0960-7692.2001.00590.x"},{"key":"e_1_2_6_9_2","first-page":"A76","article-title":"Placental sharing and birth weight in monochorionic twins: the critical role of \u2018life supporting\u2019 vascular anastomoses","volume":"13","author":"Lewi L","year":"2006","journal-title":"J Soc Gynecol Invest"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2004.04.006"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10024-004-1117-6"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)80282-0"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(05)80189-5"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/49\/14\/N01"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)70215-7"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64767-0"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-3782(92)90062-L"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2002.00799.x"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(95)91339-4"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2002.00772.x"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2000.00124.x"},{"key":"e_1_2_6_22_2","first-page":"127","article-title":"Developing criteria for establishing interrater reliability of specific items: applications to assessment of adaptive behaviour","volume":"86","author":"Cicchetti D","year":"1981","journal-title":"Am J Ment Defic"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90682-0"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.5166","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.5166","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T08:07:46Z","timestamp":1697530066000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.5166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11,2]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["10.1002\/uog.5166"],"URL":"https:\/\/doi.org\/10.1002\/uog.5166","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,11,2]]},"assertion":[{"value":"2007-08-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2007-11-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}