{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T12:32:11Z","timestamp":1759581131164},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2003,3,14]],"date-time":"2003-03-14T00:00:00Z","timestamp":1047600000000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"European Community Programme \u2018Quality of Life and Management of Living Resources\u2019","award":["QLRI-CT-1999-51230"],"award-info":[{"award-number":["QLRI-CT-1999-51230"]}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2003,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess intraobserver and interobserver variability in ovarian volume and gray\u2010scale and color flow index measurements using transvaginal, three\u2010dimensional, power Doppler ultrasonography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eleven women (22 ovaries) were examined on day 8 of controlled ovarian hyperstimulation therapy, which was part of their <jats:italic>in vitro<\/jats:italic> fertilization treatment protocol. The patients were examined twice by the first observer and once by the second observer. The acquired volume datasets were analyzed using the VOCAL<jats:sup>\u2122<\/jats:sup> imaging program, enabling the assessment of ovarian volume, vascularization index (VI), flow index (FI), vascularization flow index (VFI) and mean grayness (MG). For these parameters the intraclass (intra\u2010CC) and interclass (inter\u2010CC) correlation coefficients, within\u2010observer and between\u2010observers repeatability coefficient (<jats:italic>r<\/jats:italic>) and limits of agreement were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both intraobserver and interobserver repeatability of ovarian volume measurements were considered very good with an intra\u2010CC value of 1.00 and inter\u2010CC value of 0.99, respectively. Also VI, FI, VFI and MG measurements were repeatable by a single observer, the intra\u2010CC ranging from 0.82 to 0.91. The interobserver reproducibility was also good for VI, VFI and MG measurements (inter\u2010CC values 0.73, 0.70 and 0.81, respectively), but for FI measurements the reproducibility was poor (inter\u2010<jats:italic>CC<\/jats:italic> = 0.29, <jats:italic>r<\/jats:italic> = 7.87).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In general, the intraobserver reproducibility was better than interobserver reproducibility for all parameters. The volume assessments were reproducible both by one observer and by two separate observers. The intraobserver and interobserver variabilities were acceptable for VI, VFI and MG, whereas for FI the interobserver reproducibility was poor. Our results suggest that measurement of gray\u2010scale and color Doppler flow indices is reproducible thus allowing them to be used in clinical practice and research. Copyright \u00a9 2003 ISUOG. Published by John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.62","type":"journal-article","created":{"date-parts":[[2003,3,24]],"date-time":"2003-03-24T14:58:42Z","timestamp":1048517922000},"page":"277-282","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":93,"title":["Intraobserver and interobserver variability of ovarian volume, gray\u2010scale and color flow indices obtained using transvaginal three\u2010dimensional power Doppler ultrasonography"],"prefix":"10.1002","volume":"21","author":[{"given":"I. Y.","family":"J\u00e4rvel\u00e4","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Sladkevicius","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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