{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:54:46Z","timestamp":1791316486389,"version":"4.3.1"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T00:00:00Z","timestamp":1789776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T00:00:00Z","timestamp":1789776000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002842","name":"Chiang Mai University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002842","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To externally validate the diagnostic performance of 10 previously published fetal echocardiographic sagittal aortic\u2010arch parameters and to develop an optimal predictive model based on these parameters for the prenatal identification of neonatal coarctation of the aorta (CoA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective, multicenter diagnostic cohort study, including pregnancies with suspected fetal CoA and postnatal diagnostic confirmation. Sagittal aortic\u2010arch videoclips obtained from patients at two tertiary referral centers in Thailand between January 2014 and January 2025 were reviewed offline by a single investigator blinded to the final diagnosis to assess 10 predefined echocardiographic parameters of the aortic arch, including vascular diameters, interarterial distances, vessel angles and the presence of a shelf sign. The discriminatory performance of the 10 published predictors for neonatal CoA was evaluated using univariate binary logistic regression and receiver\u2010operating\u2010characteristics (ROC)\u2010curve analysis. A final predictive model was developed by entering the 10 sagittal aortic\u2010arch parameters into a multivariable logistic regression model and applying backward elimination to derive the model with the fewest parameters without compromising discriminatory performance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 154 fetuses included in the study, 82 (53.2%) were subsequently diagnosed with neonatal CoA. Fetuses subsequently diagnosed with neonatal CoA had a significantly longer left common carotid artery\u2013left subclavian artery (LCCA\u2013LSCA) distance (median, 3.12\u2009mm\n                      <jats:italic>vs<\/jats:italic>\n                      2.14\u2009mm;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001) and a higher prevalence of the shelf sign (74.4%\n                      <jats:italic>vs<\/jats:italic>\n                      50.0%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.002). Among individual parameters, the carotid\u2013subclavian artery index showed the highest diagnostic accuracy for predicting neonatal CoA (area under the ROC curve (AUC), 0.684 (95%\u2009CI, 0.600\u20130.767)). The final multivariable model, incorporating LCCA\u2013LSCA distance, LSCA diameter, descending aortic diameter and the presence of the shelf sign, demonstrated moderate performance (AUC, 0.749 (95%\u2009CI, 0.672\u20130.826)). At a predicted probability cut\u2010off of 0.45, the sensitivity and specificity of the combined model for the prenatal identification of neonatal CoA were 84.1% (95%\u2009CI, 74.4\u201391.3%) and 54.2% (95%\u2009CI, 42.0\u201366.0%), respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In fetuses with suspected CoA, a multiparametric predictive model based on sagittal aortic\u2010arch assessment improves prenatal diagnosis compared with previously published methods. A longer LCCA\u2013LSCA distance, the presence of the shelf sign and an increased LSCA diameter are useful for distinguishing true\u2010positive cases of CoA during fetal echocardiography. \u00a9 2026 International Society of Ultrasound in Obstetrics and Gynecology.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/uog.70321","type":"journal-article","created":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T21:26:22Z","timestamp":1789853182000},"page":"550-558","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sagittal aortic\u2010arch assessment for prenatal diagnosis of coarctation of the aorta: comparative evaluation of 10 published methods and a new predictive model"],"prefix":"10.1002","volume":"68","author":[{"given":"U.","family":"Chonnak","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine Chiang Mai University  Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7152-1952","authenticated-orcid":false,"given":"F.","family":"Tongprasert","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine Chiang Mai University  Chiang Mai Thailand"},{"name":"Fetal Center, Faculty of Medicine Chiang Mai University  Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0529-2930","authenticated-orcid":false,"given":"S.","family":"Anuwutnavin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3389-6478","authenticated-orcid":false,"given":"T.","family":"Tongsong","sequence":"additional","affiliation":[{"name":"Fetal Center, Faculty of Medicine Chiang Mai University  Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.15341"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2023.131430"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5696"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.71.1.70"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-020-02509-6"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-024-04851-7"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2022.07.010"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semperi.2022.151584"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4753"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12165190"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2009.28.12.1651"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.2307\/2531595"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.13578"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.024068"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-016-1520-6"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.7863\/ultra.15.06049"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4452"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.11228"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.27576"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1279453"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2020.1849109"}],"container-title":["Ultrasound in Obstetrics &amp; 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