{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T23:31:22Z","timestamp":1791156682216,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2010,5,5]],"date-time":"2010-05-05T00:00:00Z","timestamp":1273017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study was carried out to evaluate the perinatal outcomes of pregnancy with pregestational diabetes mellitus complicated by polyhydramnios.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This was a retrospective study of singleton pregnancies, with an antepartum diagnosis of polyhydramnios, seen at the maternal fetal medicine department of Mater Mothers' Hospital, a tertiary\u2010level facility. All pregnancies in women with pregestational diabetes with a singleton pregnancy beyond 24 weeks of gestation, from 1996 to 2006, were reviewed (\n                      <jats:italic>n<\/jats:italic>\n                      = 314), and pregnancies complicated by polyhydramnios were identified (\n                      <jats:italic>n<\/jats:italic>\n                      = 59). Pregnancy outcomes of women whose pregnancy was complicated with polyhydramnios were compared to those without this complication.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The incidence of polyhydramnios in the study population was 18.8%. Women with polyhydramnios had increased hemoglobin A1c (HbA1c) levels throughout the pregnancy, and the difference was significant during the prepregnancy period and in the third trimester (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.003 and\n                      <jats:italic>P<\/jats:italic>\n                      = 0.025, respectively). Significantly more mothers in the polyhydramnios group delivered preterm (54.2% vs. 33.3%,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.004), the majority of which were iatrogenic preterm deliveries (44.1%). More pregnancies with polyhydramnios were delivered by Cesarean section (83.0% vs. 62%;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.006), with the majority being performed electively in both groups (79.6% and 70.3%, respectively). Regardless, there were no significant differences in perinatal mortality rates, congenital abnormality rates, the incidences of low Apgar score, acidemia, hypoglycemia requiring intravenous therapy, phototherapy and ventilatory needs between the babies of the two groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Pregestational diabetic pregnancy with polyhydramnios is associated with poor diabetic control. Despite this, there is no significant increase in adverse perinatal outcome in these pregnancies, apart from a higher iatrogenic preterm birth rate. Copyright \u00a9 2010 ISUOG. Published by John Wiley &amp; Sons, Ltd.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/uog.7676","type":"journal-article","created":{"date-parts":[[2010,5,5]],"date-time":"2010-05-05T11:53:23Z","timestamp":1273060403000},"page":"338-343","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Influence of polyhydramnios on perinatal outcome in pregestational diabetic pregnancies"],"prefix":"10.1002","volume":"36","author":[{"given":"N.","family":"Idris","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. F.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Thomae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Gardener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. H.","family":"McIntyre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,8,26]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-198710000-00001"},{"key":"e_1_2_5_3_2","first-page":"21","article-title":"Polyhydramnios: ultrasonically detected prevalence and neonatal outcome","volume":"69","author":"Hill LM","year":"1987","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-199706000-00004"},{"key":"e_1_2_5_5_2","first-page":"136","article-title":"An overview of hydramnios","volume":"10","author":"Boylan P","year":"1986","journal-title":"Semin Perinatol"},{"key":"e_1_2_5_6_2","first-page":"347","volume-title":"Diabetes Mellitus in Pregnancy: Principles and Practice","author":"Hobbins JC","year":"1988"},{"key":"e_1_2_5_7_2","first-page":"F11","article-title":"Effects of maternal hyperglysemia on fetal renal function in sheep","volume":"255","author":"Smith FG","year":"1988","journal-title":"Am J Physiol"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(96)02551-1"},{"key":"e_1_2_5_9_2","first-page":"64","article-title":"Hourly fetal urine production rate in the fasting and the postprandial state of normal and diabetic pregnant women","volume":"84","author":"Yasuhi I","year":"1994","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(01)00426-2"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19990423)83:5<402::AID-AJMG12>3.0.CO;2-F"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-199908000-00014"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(88)90090-7"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-199911000-00025"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-5491.2002.00665.x"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7103.279"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-5491.2003.01017.x"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7103.275"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38043.583160.EE"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200207000-00021"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-994059"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0960-7692.2001.00560.x"},{"key":"e_1_2_5_23_2","first-page":"515","article-title":"Glycemic thresholds for spontaneous abortion and congenital malformations in insulin\u2010dependant diabetes mellitus","volume":"84","author":"Rosenn B","year":"1994","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0004-8666.2003.00094.x"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.7676","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.7676","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T05:57:00Z","timestamp":1696744620000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.7676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,26]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["10.1002\/uog.7676"],"URL":"https:\/\/doi.org\/10.1002\/uog.7676","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,8,26]]},"assertion":[{"value":"2009-10-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-08-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}